I-H-Gly-ONp·HCl CAS:17639-39-3

I-H-Gly-ONp·HCl isebenza njenge-reagent ebalulekile ekwakhiweni kwe-peptide, okwenza kube lula ukunamathela kwe-glycine kwamanye amaqembu noma izindawo ezisebenzayo. Ukuba khona kweqembu le-ONp ester kuvumela ukuthi kwenzeke ukusabela okukhethiwe kokuhlangana, okuvumela ukuhlanganiswa kwama-peptide aqukethe i-glycine namanye ama-molecule noma izindawo ngendlela elawulwayo. Le nhlanganisela iwusizo ekudaleni ama-peptide conjugates anezakhiwo ezithile njengokuqina okuthuthukisiwe, ukuncibilika, noma ikhono le-bioconjugation. Ekuthuthukisweni kwemithi, i-H-Gly-ONp·HCl ingasetshenziswa ukudala ama-peptide-drug conjugates, okungenzeka kuholele ekusebenzeni kahle kokwelapha okuthuthukisiwe, ukulethwa okuqondiwe, noma izinhlelo zokusebenza zokuxilonga. Ngaphezu kwalokho, ocwaningweni lwe-proteomics kanye ne-biochemical, i-H-Gly-ONp·HCl ithola ukusetshenziswa ekuguqulweni kwamaprotheni endaweni ethile, ekwakhiweni kwemitapo yolwazi ye-peptide, noma ekusebenzeni kwezindawo zokuhlola ezahlukahlukene ze-bioanalytical. Ukuguquguquka kwayo kanye nokuhambisana kwayo nezimo ezahlukahlukene zokuhlola kwenza kube yingxenye ebalulekile yokwembula ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Ngamafuphi, i-H-Gly-ONp·HCl imele ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide namaprotheni anezakhiwo ezithile kanye nokusebenza, ngaleyo ndlela inikele ekuthuthukisweni kwezokwelapha, ubuchwepheshe be-bio, kanye namasu okuhlanganisa i-bio.