I-H-Glu-(OBut)-OMe CAS: 6234-01-1.

I-H-Glu-(OBut)-OMe isebenza njengesisekelo esibalulekile ekwakheni ama-peptide, okuvumela ukwakhiwa kwama-peptide anezakhiwo ezilungiselelwe ngenxa yokuba khona kwamaqembu e-butyl kanye ne-methyl ester. Lokhu kuguqulwa kuthinta ukusebenzisana kwe-hydrophobic, ukuzinza, kanye nokusebenza kwamakhemikhali kwe-peptide, okwenza kube wusizo ekwakheni ama-peptide anokuvuleka kwe-membrane okuthuthukisiwe noma amakhono athile okukhomba. Ekuthuthukisweni kwemithi, le nhlanganisela ingasetshenziswa ukudala izidakamizwa ezisekelwe kuma-peptide ezinokuqina okuthuthukisiwe kanye nokutholakala kwezinto eziphilayo, okungenzeka kuholele ekusebenzeni kahle kokwelapha okuthuthukisiwe. Ngaphezu kwalokho, ocwaningweni lwe-proteomics kanye nolwe-biochemical, i-H-Glu-(OBut)-OMe ithola izinhlelo zokusebenza ekutadisheni ukusebenzisana kwamaprotheni nama-protein, ekuphenyeni imisebenzi ye-enzyme, nasekuhloleni amandla okugoqa amaprotheni. Izakhiwo zayo ezihlukile zivumela abacwaningi ukuthi bahlole ubunzima bezinqubo zamaseli kanye nezindlela zezifo, okufaka isandla ekuthuthukisweni kokuqonda impilo kanye ne-pathology. Ukuguquguquka kanye nokuhambisana kwale nhlanganisela nezimo ezahlukahlukene zokuhlola kwenza kube yingxenye ebalulekile yokwembula ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Ngamafuphi, i-H-Glu-(OBut)-OMe imele ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide anezakhiwo ezithile futhi ahlukanise izindlela eziyisisekelo zezinqubo zezinto eziphilayo, ngaleyo ndlela enikela ekuthuthukisweni kwezokwelapha kanye ne-biotechnology.