I-HD-Arg-OMe·2HCl CAS:78851-84-0

I-HD-Arg-OMe·2HCl idlala indima ebalulekile ekuhlanganisweni nasekuguqulweni kwe-peptide ngenxa yekhono layo lokungenisa i-N-methyl-D-arginine ezakhiweni ze-peptide. Lokhu kuguqulwa kwenza abacwaningi bakwazi ukutadisha nokushintsha izakhiwo zama-peptide namaprotheni, okwenza kube lula ukuthuthuka ekutholakaleni kwezidakamizwa kanye nophenyo lwezinqubo zezinto eziphilayo. Ekuthuthukisweni kwemithi, i-HD-Arg-OMe·2HCl inegalelo ekukhiqizweni kwezidakamizwa ezisekelwe kuma-peptide nama-bioconjugates. Ukusebenza kwayo kanye nokucaciswa kwayo kuvumela ukuphathwa okunembile kwezakhiwo ze-peptide, okubalulekile ekwakheni ama-ejenti amasha okwelapha anezicelo ezingaba khona ekulethweni kwemithi okuqondiwe kanye nemithi enembile. Ngaphezu kwalokho, ocwaningweni lwe-biochemical, i-HD-Arg-OMe·2HCl inikeza ososayensi izindlela zokuhlola nokulawula imisebenzi kanye nokusebenzisana kwama-peptide namaprotheni. Ukusetshenziswa kwayo ekuguquleni ukulandelana kwama-peptide kuveza ukuqonda ngezinqubo zezinto eziphilayo kanye nezinhloso ezingaba khona zokuthuthukiswa kwemithi, ngaleyo ndlela kunegalelo ekuqondeni kabanzi izindlela zama-molecule ezintweni eziphilayo. Ukunamathela ezimisweni zokuphepha zelebhu ezimisiwe kanye neziqondiso zokuphatha kubalulekile lapho usebenza ne-HD-Arg-OMe·2HCl ukuqinisekisa ukusetshenziswa okufanele nokunciphisa izingozi ezihlobene nama-reagent amakhemikhali. Ukuqonda ukusabela okuthile kanye nokusetshenziswa kwe-HD-Arg-OMe·2HCl ngaphakathi komongo wokwenziwa nokuguqulwa kwe-peptide kubalulekile ekwenzeni izivivinyo eziphumelelayo nokufeza imiphumela yesayensi efiselekayo.