I-HD-Ala-OMe·HCL CAS:14316-06-4

I-HD-Ala-OMe·HCl idlala indima ebalulekile ekuhlanganisweni nasekuguqulweni kwe-peptide ngenxa yekhono layo lokungenisa i-N-methyl-D-alanine ezakhiweni ze-peptide. Lokhu kuguqulwa kuvumela abacwaningi ukuthi batadishe futhi bashintshe izakhiwo zama-peptide namaprotheni, okuvumela ukuthuthuka ekutholakaleni kwemithi kanye nophenyo lwezinqubo zebhayoloji. Ekuthuthukisweni kwemithi, i-HD-Ala-OMe·HCl inegalelo ekukhiqizweni kwemithi esekwe kuma-peptide nama-bioconjugates. Ukusabela kwayo kanye nokucaciswa kwayo kuvumela ukuphathwa okunembile kwezakhiwo ze-peptide, okubalulekile ekwakheni ama-ejenti amasha okwelapha anezicelo ezingaba khona ekulethweni kwemithi okuqondiwe kanye nemithi enembile. Ngaphezu kwalokho, ocwaningweni lwe-biochemical, i-HD-Ala-OMe·HCl inikeza ososayensi izindlela zokuhlola nokulawula imisebenzi kanye nokusebenzisana kwama-peptide namaprotheni. Ukusetshenziswa kwayo ekuguquleni ukulandelana kwama-peptide kungaholela ekuqondeni izinqubo zebhayoloji kanye nezinhloso ezingaba khona zokuthuthukiswa kwemithi, ngaleyo ndlela kufake isandla ekuqondeni kabanzi kwezindlela zama-molecule ezintweni eziphilayo. Lapho usebenza ne-HD-Ala-OMe·HCl, ukunamathela ezimisweni zokuphepha zelebhu ezimisiwe kanye neziqondiso zokuphatha kubalulekile ukuqinisekisa ukusetshenziswa okufanele nokunciphisa izingozi ezihlobene nama-reagent amakhemikhali. Ukuqonda ukusebenza okuqondile kanye nokusetshenziswa kwe-HD-Ala-OMe·HCl ngaphakathi komongo wokwenziwa nokuguqulwa kwe-peptide kubalulekile ekwenzeni izivivinyo eziphumelelayo nokufeza imiphumela yesayensi efiselekayo.