I-Griseofulvin CAS:126-07-8 Umhlinzeki Womkhiqizi

I-Griseofulvin iyi-antibiotic elwa namagciwane engeyona i-polyene class; ingavimbela kakhulu i-mitosis yamaseli e-fungal futhi iphazamise ukwakheka kwe-DNA ye-fungal; ingabopha ne-tubulin ukuvimbela ukuhlukaniswa kwamaseli e-fungal. Isetshenziswe kwezokwelapha kusukela ngo-1958 futhi okwamanje isetshenziswa kabanzi ekwelapheni ukutheleleka kwe-fungal kwesikhumba kanye ne-stratum corneum ngemiphumela enamandla yokuvimbela ku-Trichophyton rubrum kanye ne-Trichophyton tonsorans, njll. I-Griseofulvin ayiyona nje i-antibiotic esetshenziswa kabanzi ekwelapheni ukutheleleka kwe-fungal kwesikhumba kanye ne-cuticle, kodwa futhi isetshenziswa kwezolimo ekuvimbeleni nasekuphatheni izifo ze-fungal; isibonelo, inamandla akhethekile ekwelapheni uhlobo lwe-candidiasis kuma-apula olungabangela ukutheleleka ngesikhathi sokuthunyelwa kwempova.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

I-Griseofulvin iyi-spirobenzofuran ekhiqizwa izinhlobo eziningana ze-Penicillium, eyaqala ukuhlukaniswa ngawo-1930 yiqembu likaRaistrick. I-Griseofulvin iyi-ejenti ekhethiwe yokukhunta esetshenziselwa ukwelapha izifo zesikhumba ezilwaneni nakubantu. I-Griseofulvin isebenza ngokubopha ku-tubulin yesikhunta futhi ivimbele i-mitotic spindle. Amandla e-Griseofulvin okubopha ku-keratin abhekwa njengesici esibalulekile sokufinyelela kwe-metabolite ku-fungi ye-dermatophytic. Muva nje, i-griseofulvin isibe uphawu olubalulekile lwe-phenotypic ku-Penicillium taxonomy. Iwumuthi wokukhunta. Isetshenziswa kokubili ezilwaneni nakubantu, ukwelapha izifo ze-rigworm zesikhumba nezinzipho. Itholakala ku-mold i-Penicillium griseofulvum. Izinto ezingcolisayo zemvelo; Izinto ezingcolisayo zokudla.

Isampula Yomkhiqizo

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C17H17ClO6
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe
Inombolo ye-CAS	126-07-8
Ukupakisha	25KG
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.