I-Fmoc -Glu(OBut)-OSu CAS:101214-22-6

I-Fmoc-Glu(OBut)-OSu ithola usizo olukhulu ekuhlanganisweni kwe-peptide, ikakhulukazi ekusetshenzisweni kwe-bioconjugation kanye ne-peptide immobilization. Ifomu layo elisebenzayo njenge-N-hydroxysuccinimide ester lenza ukusabela kokuhlanganisa okukhethiwe nama-amine ayinhloko akhona kuma-peptide, amaprotheni, noma ezindaweni. Abacwaningi basebenzisa i-Fmoc-Glu(OBut)-OSu ekuhlanganiseni ama-peptide kuma-molecule athwalayo, izindawo, noma amanye ama-peptide, okwenza kube lula ukuthuthukiswa kwezokwelapha okusekelwe kuma-peptide, ukuxilonga, kanye nezinto eziphilayo. Ngaphezu kwalokho, i-Fmoc-Glu(OBut)-OSu isebenza njengethuluzi elibalulekile ocwaningweni lwe-biology yamakhemikhali kanye ne-proteomics, okuvumela ukuguqulwa kwamaprotheni noma ama-peptide endaweni ethile ukuze kwenziwe izifundo ezisebenzayo noma ukuhlanzwa kwe-affinity. Ukuhambisana kwayo namakhemikhali ahlukahlukene okuhlanganisa kanye nezimo zokusabela okuncane kuthuthukisa ukuguquguquka kwayo ezinhlelweni zocwaningo ezahlukahlukene. Ngaphezu kwalokho, i-Fmoc-Glu(OBut)-OSu idlala indima ebalulekile ekuhlanganisweni kwama-peptide mimetics, ama-peptide dendrimers, kanye nezinye izakhiwo eziyinkimbinkimbi ezisekelwe kuma-peptide. Ukusabela kwayo okulawulwayo kanye nokuzinza kwenza kube ukukhetha okuthandwayo kokusabela kokuhlanganiswa kwe-peptide okukhethayo, okuvumela abacwaningi ukuthi baklame ngokunembile izakhiwo ze-peptide ngemisebenzi eklanyelwe bona. Ngamafuphi, i-Fmoc-Glu(OBut)-OSu imele njengethuluzi eliguquguqukayo nelibalulekile kumakhemikhali e-peptide, inika abacwaningi amandla okwenza ukusabela kokuhlanganiswa kwe-peptide okukhethiwe futhi bandise ububanzi bezicelo ocwaningweni olusekelwe ku-peptide, i-biotechnology, kanye nokuthuthukiswa kwemithi.