I-Fmoc-Gln-OH CAS:118609-68-0

I-Fmoc-Gln-OH isebenza njengethuluzi eliguquguqukayo ekuhlanganisweni kwe-peptide, ikakhulukazi ekwakheni ama-peptide aqukethe i-glutamine ngokunemba. Iqembu elivikela i-Fmoc livikela iqembu lama-amino, liqinisekisa ukusabela okukhethiwe ngesikhathi sokuhlanganiswa kwe-peptide. Abacwaningi basebenzisa kakhulu i-Fmoc-Gln-OH ekwakhiweni kwama-peptide ngezinhlelo zokusebenza ezahlukahlukene, okuhlanganisa ukuthuthukiswa kwezokwelapha okusekelwe ku-peptide, izinto eziphilayo, kanye nama-peptide anezimpawu ezithile zesakhiwo. Ukuhambisana kwayo nezindlela ezijwayelekile zokwenziwa kwe-peptide, kokubili kumasu esigaba esiqinile kanye nesigaba sesisombululo, kuthuthukisa ukuguquguquka kwayo emizamweni yocwaningo ehlukahlukene. Ukususwa okulawulwayo kwamaqembu avikelayo kuvumela ukufakwa kwe-glutamine ngamasu okulandelana kwe-peptide, kwandisa ububanzi bama-peptide angenziwa. Ngaphezu kwalokho, i-Fmoc-Gln-OH ithola usizo ezifundweni ezihlobene nobunjiniyela bamaprotheni, i-peptide mimetics, kanye nokwakhiwa kwama-peptide asebenzayo. Ukusetshenziswa kwayo ngamasu kwenza kube lula ukuphathwa kwe-glutamine reactivity ngendlela enembile, okunikeza abacwaningi ithuluzi eliwusizo lokuklama ama-peptide ngokuguqulwa okulungiselelwe. Ngamafuphi, i-Fmoc-Gln-OH imele njengethuluzi eliyisisekelo nelibalulekile kumakhemikhali e-peptide, inika amandla abacwaningi ukuthi bahlole futhi bashintshe ukusabela kwe-glutamine ezinhlobonhlobo zezicelo zesayensi, ikakhulukazi ukugxila kuma-peptide aqukethe le amino acid ebalulekile.