I-Fmoc-Asn-OH CAS:71989-16-7

I-Fmoc-Asn-OH idlala indima ebalulekile ekwakhiweni kwe-peptide, ikakhulukazi ekuhlanganisweni okulawulwayo kwama-peptide aqukethe i-asparagine. Iqembu elivikela i-Fmoc livikela iqembu lama-amino le-asparagine, livimbela ukusabela okungafuneki ngesikhathi sokuhlanganiswa kwe-peptide. Le nhlanganisela isetshenziswa kakhulu ekwakhiweni kwama-peptide ezifundweni zezinto eziphilayo, ekuthuthukisweni kwemithi, kanye nasekuklanyweni kwama-peptide asebenzayo. Ukuguquguquka kwe-Fmoc-Asn-OH kudlulela ekusetshenzisweni kwayo ekwakheni ama-peptide anezinsalela ezithile ze-asparagine, okufaka isandla ekuthuthukisweni kwama-peptide anezakhiwo nemisebenzi eklanyelwe. Abacwaningi basebenzisa ukuhambisana kwayo nezindlela ezijwayelekile zokwenziwa kwe-peptide, beyisebenzisa kumasu ahlukahlukene okwenziwa kwe-peptide. Ukuqina kwayo kanye nokulula kokuphathwa kwayo kwenza kube ukukhetha okuthandwayo kokukhiqiza ama-peptide anezinguquko eziqondile. Ngaphezu kwalokho, i-Fmoc-Asn-OH ithola usizo ekwakhiweni kwama-peptide ezinto eziphilayo, ucwaningo lwe-proteomics, kanye nokutadisha izinqubo zamaseli. Ukususwa kokuvikela okulawulwayo kweqembu le-Fmoc kuvumela ukufakwa kwe-asparagine ngamasu okulandelana kwe-peptide. Ngamafuphi, i-Fmoc-Asn-OH imele njengethuluzi eliguquguqukayo nelibalulekile kumakhemikhali e-peptide, ithuthukisa ucwaningo kanye nezinhlelo zokusebenza emikhakheni eyahlukene yesayensi.