-
I-Ofloxacin CAS:82419-36-1
I-Ofloxacin iyi-antibiotic yokwenziwa ye-fluoroquinolone enomsebenzi onamandla wokulwa namagciwane ngokumelene namagciwane ahlukahlukene angenayo i-gram kanye ne-gram. Ivimbela i-bacterial DNA gyrase kanye ne-topoisomerase IV enzymes, iphazamisa ukuphindaphindeka kwe-DNA futhi iholele ekufeni kwamangqamuzana amagciwane. Itholakala emithini yomlomo, yangaphandle, kanye ne-intravenous, i-ofloxacin ivame ukunqunyelwa ekwelapheni izifo ezahlukahlukene, okuhlanganisa izifo zokuphefumula, izifo zomchamo, izifo zesikhumba nezicubu ezithambile, kanye nezifo ezithathelwana ngocansi. Umsebenzi wayo obanzi, i-pharmacokinetics enhle, kanye nokusebenza kahle kwezokwelapha kwenza i-ofloxacin ibe yindlela yokwelapha ebalulekile kokubili ezindaweni zomphakathi kanye nasezibhedlela.
-
I-Norfloxacin CAS: 70458-96-7
I-Norfloxacin iyi-antibiotic yokwenziwa ye-fluoroquinolone enomsebenzi wokulwa namagciwane we-spectrum ebanzi ngokumelene namagciwane angenayo i-gram kanye namanye angenayo i-gram. Ivimbela i-bacterial DNA gyrase kanye ne-topoisomerase IV, ama-enzyme abalulekile ahilelekile ekuphindaphindweni nasekulungisweni kwe-DNA, ngaleyo ndlela ibe nemiphumela yokubulala amagciwane. I-Norfloxacin iyatholakala emithini yomlomo, kufaka phakathi amaphilisi kanye ne-suspensions, yokwelapha izifo ezahlukahlukene zamagciwane, njengokutheleleka komgudu womchamo, izifo zamathumbu, izifo zokuphefumula, kanye nezifo ezithathelwana ngocansi. Ivame ukunikezwa ngenxa yokusebenza kwayo kahle, ukubekezeleleka, kanye nohlelo lokulinganisa olulula.
-
I-Nisin CAS:1414-45-5
I-Nisin iyi-peptide yemvelo yokulwa namagciwane ekhiqizwa izinhlobo ezithile zebhaktheriya i-Lactococcus lactis. Ingesigaba sama-lanbiotic, abonakala ngesakhiwo sawo esiyingqayizivele esiqukethe i-lanthionine kanye nama-amino acid e-methyllanthionine. I-Nisin ibonisa umsebenzi onamandla wokulwa namagciwane ngokumelene nezinhlobo eziningi zamabhaktheriya ane-gram-positive, okuhlanganisa namagciwane atholakala ekudleni njenge-Listeria monocytogenes kanye ne-Staphylococcus aureus. Ngenxa yokuqina kwayo ekushiseni kanye nokuhambisana nezimo ezahlukahlukene zokucubungula ukudla, i-nisin isetshenziswa kabanzi njengesivikelo semvelo embonini yokudla ukuvimbela ukukhula kwamabhaktheriya nokwandisa impilo yeshelufu yemikhiqizo ebolayo.
-
I-Oxytetracycline dihydrate CAS:6153-64-6
I-Oxytetracycline dihydrate iwuhlobo lwe-oxytetracycline, i-antibiotic ene-spectrum ebanzi eyingxenye ye-tetracycline. Njengamanye ama-tetracycline, ivimbela ukwakheka kwamaprotheni ebhaktheriya ngokubopha ku-30S ribosomal subunit, ngaleyo ndlela isebenzise imiphumela ye-bacteriostatic ngokumelene nohlu olubanzi lwamagciwane ane-gram-positive kanye ne-gram-negative. I-Oxytetracycline dihydrate ifana ne-oxytetracycline kodwa iqukethe ama-molecule amanzi amabili esakhiweni sayo sekristalu. Itholakala ezinhlobonhlobo zemithi yokusetshenziswa kwabantu kanye nezilwane.
-
I-Ornidazole CAS:16773-42-5
I-Ornidazole iyi-antibiotic yokwenziwa ye-nitroimidazole kanye ne-antiprotozoal ejenti enomsebenzi obanzi wokulwa namagciwane angenawo umoya kanye ne-protozoa. Isebenza ngokulimaza i-DNA yamagciwane abangela izifo ezincane, okuholela ekufeni kwawo. I-Ornidazole itholakala emithini yomlomo, kufaka phakathi amaphilisi kanye nemithi yokumiswa, yokwelapha izifo ezahlukahlukene, njenge-bacterial vaginosis, i-trichomoniasis, i-giardiasis, kanye ne-amoebiasis. Ngokuvamile inikezwa ngenxa yokusebenza kwayo kahle, ukubekezeleleka, kanye nohlelo lokulinganisa olulula.
-
I-Oxacillin sodium salt monohydrate CAS:7240-38-2
I-Oxacillin sodium salt monohydrate iyi-antibiotic ye-beta-lactam ene-spectrum encane, efana ne-oxacillin sodium salt, ene-molecule yamanzi eyodwa esakhiweni sayo sekristalu. Ifana ne-methicillin ne-nafcillin, iyasebenza ngokumelene ne-staphylococci ekhiqiza i-penicillinase. I-Oxacillin sodium salt monohydrate ivimbela ukwakheka kodonga lwamaseli ebhaktheriya ngokuphazamisa ukuxhumanisa kwe-peptidoglycan, isebenzise imiphumela yokubulala amagciwane ezidakamizweni ezisengozini. Itholakala ezinhlotsheni ezijovwayo zokuphathwa ngemithambo yegazi noma nge-intramuscular, ivame ukusetshenziswa ezindaweni zokunakekelwa kwempilo ekwelapheni izifo ezibangelwa izinhlobo ze-Staphylococcus aureus ekhiqiza i-penicillinase.
-
I-Pefloxacin mesylate CAS:70458-95-6
I-Pefloxacin mesylate iyi-antibiotic yokwenziwa ye-fluoroquinolone enomsebenzi wokulwa namagciwane we-spectrum ebanzi ngokumelene namagciwane e-gram-positive kanye ne-gram-negative. Isebenza ngokuvimbela ukwakheka kwe-DNA yamagciwane ngokusebenzisana kwayo nama-enzyme afana ne-DNA gyrase kanye ne-topoisomerase IV, okuholela emiphumeleni yokubulala amagciwane. I-Pefloxacin mesylate itholakala ezinhlotsheni ezahlukene zemithi zokuphathwa ngomlomo kanye nangomjovo, inikeza izinketho zokwelapha ezisebenzayo zezifo eziningi zamagciwane.
-
Novobiocin sodium usawoti CAS:1476-53-5
I-Novobiocin sodium salt iyi-antibiotic etholakala kumagciwane etholakala emndenini we-coumarin, ekuqaleni eyayihlukaniswe nezinhlobo ze-Streptomyces. Ibonisa umsebenzi we-antibacterial we-spectrum ebanzi, ikakhulukazi ngokumelene namagciwane ane-gram-positive, ngokuvimbela i-DNA gyrase, i-enzyme ebalulekile ehilelekile ekuphindaphindweni kwe-DNA kanye nokubhalwa kwayo. I-Novobiocin ivame ukusetshenziswa emalabhorethri e-microbiology ngenxa yokuvimbela kwayo i-Staphylococcus aureus kanye nezinye i-staphylococci ezine-coagulase-positive, okwenza kube ithuluzi eliwusizo lokuhlonza amagciwane kanye nokuhlolwa kokuzwela kwamagciwane.
-
I-Nitrocefin CAS:41906-86-9
I-Nitrocefin iyi-substrate ye-cephalosporin ye-chromogenic esetshenziswa ku-microbiology ukuthola umsebenzi we-beta-lactamase kumabhaktheriya. Isebenza njengethuluzi lokuxilonga lokuhlonza amagciwane akhiqiza ama-enzyme e-beta-lactamase akwazi ukumanzisa ama-antibiotic e-beta-lactam, njenge-penicillins kanye ne-cephalosporins. I-Nitrocefin ishintsha umbala kusukela kophuzi kuya kobomvu lapho kukhona i-beta-lactamase, okuvumela ukubonwa okusheshayo komsebenzi we-enzyme. Lesi sici senza i-nitrocefin ibe ithuluzi eliwusizo emalabhorethri emitholampilo yokuhlola amabhaktheriya ahlukanisiwe kanye nokuqondisa izinqumo zokwelapha ngama-antibiotic.
-
I-Oleandomycin phosphate CAS:7060-74-4
I-Oleandomycin phosphate iyi-antibiotic yama-macrolide etholakala ku-Streptomyces antibioticus, eyaziwa ngomsebenzi wayo wokulwa namagciwane we-spectrum ebanzi ngokumelene namagciwane ane-gram-positive. Ivimbela ukwakheka kwamaprotheni amabhaktheriya ngokubopha ku-50S ribosomal subunit, okuholela emiphumeleni ye-bacteriostatic. I-Oleandomycin phosphate ivame ukusetshenziswa kwezokwelapha zezilwane ekwelapheni izifo zamabhaktheriya emfuyweni nasezinkukhu. Itholakala emafomulini afanele ukusetshenziswa ngomlomo ukubhekana nezifo zokuphefumula, izinkinga zesisu, nezinye izifo zamabhaktheriya ezithinta izilwane.
-
I-Natamycin (i-Pimaricin) CAS:7681-93-8
I-Natamycin, eyaziwa nangokuthi i-pimaricin, iyi-antifungal eyenzeka ngokwemvelo ekhiqizwa yi-bacterium Streptomyces natalensis. Isetshenziswa kabanzi njengesivikelo sokudla ukuvimbela ukukhula kwesikhunta nemvubelo emikhiqizweni eyahlukene yobisi, inyama, kanye nezinto ezibhakiwe. I-Natamycin iyasebenza ngokumelene nezinhlobo eziningi zesikhunta, okuhlanganisa i-Aspergillus, i-Penicillium, kanye ne-Fusarium, kuyilapho iphephile ukusetshenziswa ngabantu. Lo mkhiqizo uyaziwa ngokuzinza kwawo, ukumelana nokushisa, kanye nomthelela omncane ezimpahleni ze-organoleptic zokudla, okwenza kube ukukhetha okuthandwayo ekukhiqizeni nasekulondolozeni ukudla.
-
I-Nadifloxacin CAS:124858-35-1
I-Nadifloxacin iyi-antibiotic ye-fluoroquinolone esetshenziswa ekwelapheni izifo zesikhumba ezahlukahlukene. Ibonisa umsebenzi onamandla wokubulala amagciwane ngokumelene namagciwane ahlukahlukene, ikakhulukazi lawo ahilelekile ku-acne vulgaris kanye ne-dermatitis. I-Nadifloxacin isebenza ngokuvimbela ukuphindaphindeka kwe-DNA yamagciwane, ngaleyo ndlela iqede ngempumelelo amagciwane ayingozi ebusweni besikhumba. Lo mkhiqizo utholakala ngesimo sama-creams, ama-gel, noma ama-lotion okusetshenziswa kwangaphandle. Ibekezelelwa kahle futhi ivame ukunqunywa ochwepheshe bezempilo ngenxa yokusebenza kwayo kahle kanye nephrofayili yokuphepha ezimweni zesikhumba.
