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3,3-Dimethyl-1-Butyne CAS:917-92-0
I-3,3-Dimethyl-1-butyne iyinhlanganisela yamakhemikhali ephawulekayo ngesakhiwo sayo sezibopho ezintathu kanye namaqembu amabili e-methyl anamathele kuma-athomu e-carbon esibopho sezibopho ezintathu. Ngokuvamile ibizwa ngokuthi i-tetramethylethyne futhi isetshenziswa ezinqubweni ezahlukene zokwenziwa kwamakhemikhali.
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I-6-Chloro-3-methyluracil CAS:4318-56-3
I-6-Chloro-3-methyluracil iyi-derivative ye-uracil, isisekelo se-pyrimidine, enamaqembu e-chlorine ne-methyl anamathele ezindaweni ezithile eringini ye-uracil. Lokhu kuguqulwa kunikeza izakhiwo zamakhemikhali nezebhayoloji ezihlukile kule nhlanganisela, okwenza ibaluleke kakhulu kumakhemikhali ezokwelapha kanye nocwaningo lwe-biochemical. Isakhiwo se-6-Chloro-3-methyluracil sithonya ukusebenzisana kwayo ngaphakathi kwezinhlelo zezinto eziphilayo, ikakhulukazi ekwakhiweni kwe-nucleic acid kanye nokuvinjelwa kwe-enzyme, okuyizici ezibalulekile ekwakhiweni kwemithi kanye nentuthuko yokwelapha.
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I-4-Isothiocyanato-2-(trifluoromethyl)benzonitrile CAS:143782-23-4
I-4-Isothiocyanato-2- (trifluoromethyl)benzonitrile iyinhlanganisela yamakhemikhali ebonakala ngeqembu elisebenzayo le-isothiocyanate elixhunywe endandatho ye-benzene ethathelwe indawo yi-trifluoromethyl. Isetshenziswa ngokuyinhloko njengebhloko yokwakha eguquguqukayo ekuhlanganisweni kwezinto eziphilayo, okuvumela ukudalwa kwezakhiwo eziyinkimbinkimbi zama-molecule nezinto ezisebenzayo.
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![I-Exit(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacidmethyste CAS:171489-59-1](https://cdn.globalso.com/xindaobiotech/5EVBWZZXL9LE4FA@55921.png)
I-Exit(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylicacidmethyste CAS:171489-59-1
(1R,3R)-1-(1,3-Benzodioxol-5-yl)-2-(chloroacetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester, efushaniswe ngokucaca, iyinhlanganisela yamakhemikhali eyaziwa ngokwakhiwa kwayo okuyinkimbinkimbi kwama-molecule kanye nezicelo ezingaba khona kumakhemikhali ezokwelapha. Le nhlanganisela ihlanganisa umongo we-pyridoindole nendandatho ye-tetrahydrofuran ehlanganiswe neqembu le-chloroacetyl kanye nengxenye ye-1,3-benzodioxol-5-yl, equkethe ukusebenza kwe-methyl ester. Lezi zakhi zesakhiwo zinikeza izindlela zokuguqulwa kwesakhiwo okuhlukahlukene kanye nophenyo olunzulu lwezinto eziphilayo.
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I-Candesartan ester ephakathi C3 CAS:136285-65-9
I-Candesartan ester intermediate C3 iyinhlanganisela ebalulekile ekwakhiweni kwe-Candesartan cilexetil, i-angiotensin II receptor antagonist esetshenziswa kakhulu ekwelapheni umfutho wegazi ophakeme kanye nokwehluleka kwenhliziyo okukhungathekile. Le intermediate idlala indima ebalulekile embonini yezemithi ngenxa yendima yayo njengesandulela ekwakhiweni kwe-Candesartan cilexetil okuphumelelayo.
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I-Linagliptin interMediate F CAS:853029-57-9
I-Linagliptin Intermediate F iyisithako esibalulekile ekwakhiweni kwe-linagliptin, i-dipeptidyl peptidase-4 (DPP-4) inhibitor enamandla esetshenziswa ekwelapheni isifo sikashukela sohlobo 2. Lesi sithako sidlala indima ebalulekile embonini yezemithi ngenxa yesakhiwo sayo samakhemikhali kanye nokusebenza kwayo. I-Linagliptin, eyaziwa ngamakhemikhali ngokuthi (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-(2,4,5-trifluorophenyl)-1,2-dihydroquinazolin-2(3H)-one, inemiphumela yayo yokwelapha ngokuvimbela umsebenzi we-enzyme ye-DPP-4, ngaleyo ndlela ithuthukise amazinga ama-hormone e-incretin njenge-GLP-1 (glucagon-like peptide-1). Lokhu kuholela ekuthuthukisweni kokulawulwa kwe-glycemic ezigulini ezinesifo sikashukela.
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I-Candesartan Cilexetil Impurity 8 CAS:139481-28-0
I-Candesartan Cilexetil Impurity 8 ingumkhiqizo ovela ngemuva kokwenziwa kwe-Candesartan cilexetil, i-angiotensin II receptor antagonist esetshenziswa kakhulu ukuphatha umfutho wegazi ophakeme kanye nokwehluleka kwenhliziyo. Naphezu kokuthi ayidingeki ekwakhiweni kokugcina kwemithi, ukuqonda nokulawula amaphrofayili okungcola kubalulekile ekuqinisekiseni ukuphepha komkhiqizo, ukusebenza kahle, kanye nokuhambisana nemithetho.
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![I-BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER CAS:57113-90-3](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG299.png)
I-BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-3-NITRO-METHYL ESTER CAS:57113-90-3
I-BENZOIC ACID, 2-[[(1,1-DIMETHYLETHOXY)CARBONYL]-3-NITRO-METHYL ESTER iyinhlanganisela yamakhemikhali ephawulekayo ngesakhiwo sayo esiyinkimbinkimbi sama-molecule kanye nezicelo ezingaba khona zemithi. Le nhlanganisela ihlanganisa ingqikithi ye-benzoic acid nengxenye ye-carbamate equkethe iqembu le-dimethylethoxy kanye nokusebenza kwe-nitro-methyl ester, okwenza ibaluleke kakhulu kumakhemikhali wezokwelapha kanye nocwaningo lwe-biochemical ngenxa yezimfanelo zayo ezihlukile zesakhiwo kanye nemisebenzi engaba khona yezinto eziphilayo.
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i-pyridine-3-sulfonyl chloride CAS:16133-25-8
I-Pyridine-3-sulfonyl chloride iyinhlanganisela yamakhemikhali eyaziwa ngokusetshenziswa kwayo okuhlukahlukene ekuhlanganisweni kwezinto eziphilayo kanye nocwaningo lwemithi. Le nhlanganisela, ebizwa nangokuthi i-picolinoyl chloride, ine-pyridine core ethathelwe indawo yiqembu le-sulfonyl chloride endaweni ye-3, okwenza ibaluleke kakhulu ngenxa yokusebenza kwayo okuhlukile kanye nokusetshenziswa kwayo okungenzeka ezinqubweni ezahlukahlukene zamakhemikhali.
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5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile CAS:1240948-77-9
I-5-(2-Fluorophenyl)-1H-pyrrole-3-carbonitrile iyinhlanganisela yamakhemikhali ehlukaniswa ngesakhiwo sayo sama-molecule kanye nokusetshenziswa okungenzeka kumakhemikhali ezokwelapha kanye nokwakheka kwezinto eziphilayo. Le nhlanganisela ifaka i-pyrrole core ethathelwe indawo yiqembu le-fluorophenyl kanye neqembu le-cyano ezindaweni ezithile, okwenza ibaluleke kakhulu ngenxa yokuhluka kwayo kwesakhiwo kanye nemisebenzi engaba khona yezinto eziphilayo.
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I-Vonoprazan CAS:881681-00-1
I-Vonoprazan iyinhlanganisela yemithi eyaziwa ngezakhiwo zayo ezinamandla zokucindezela i-asidi yesisu, iyenza ihluke kuma-proton pump inhibitors (PPIs) endabuko ngenxa yendlela yayo yokusebenza eyingqayizivele. Le nhlanganisela ivimbela i-H+, K+-ATPase proton pump emaseli e-parietal esiswini ngokunemba okuphezulu nokusebenza kahle, okuholela ekucindezelweni okujulile nokuqhubekayo kwe-asidi.
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I-N-(4-CYANO-PHENYL)-GLYCINE CAS:42288-26-6
I-N-(4-Cyano-phenyl)-glycine iyinhlanganisela yamakhemikhali ebonakala ngesakhiwo sayo sama-molecule kanye nokusetshenziswa okungenzeka emikhakheni eyahlukahlukene, ikakhulukazi kumakhemikhali ezokwelapha kanye nocwaningo lwe-biochemical. Le nhlanganisela ihlanganisa iqembu le-phenyl nengxenye ye-glycine, okwenza ibaluleke ngenxa yokwakheka kwayo okuhlukile kanye nemisebenzi engaba khona yezinto eziphilayo.
