Empagliflozin CAS:864070-44-0 Umkhiqizi Supplier

I-Empagliflozin iyinoveli, enamandla futhi ekhetha i-SGLT-2 inhibitor, ithuthukisa ukulawulwa kwe-glycemic kanye nezici ze-metabolic syndrome kumagundane anesifo sikashukela. ibangela ukuthi ushukela osegazini ukhishwe yizinso futhi ukhishwe emchamweni.I-Empagliflozin ingabangela ukuphelelwa amanzi emzimbeni futhi iholele ekwehleni komfutho wegazi, okuholela ezigulini ezinesiyezi noma ukuquleka kanye nokwehla kokusebenza kwezinso.Ingozi yeziguli esezikhulile, ikakhulukazi lezo ezinokukhubazeka kwe-renal kanye nama-diuretics, ibonakala inkulu.I-FDA idinga ukuthi u-Boehring no-Eli Lilly benze izifundo ezine zangemva kokumaketha: ukuhlolwa okuphelele okuqhubekayo kwemiphumela yenhliziyo nemithambo yegazi, ukuhlolwa kwe-pharmacokinetics kwezingane kanye ne-pharmacodynamics, ukuphepha kwezingane kanye nempumelelo ukuhlolwa, ukuhlolwa kobuthi bomuthi (ikakhulukazi umphumela wokusebenza kwezinso, amathambo nokukhula nokuthuthuka).