I-Duloxetine HCL CAS:136434-34-9 Umkhiqizi Supplier

I-Duloxetine HCL uhlobo lukasawoti lwesidakamizwa esilwa nokucindezeleka i-duloxetine.Ithuthukiswe ngempumelelo yi-Eli Lilly Company.Umphumela wayo we-pharmacological uyafana ne-duloxetine.I-Duloxetine hydrochloride iwuhlobo olusha lwe-dual inhibitor ekhethiwe ye-5 hydroxy trptamine (5-HT) kanye ne-norepinephrine reuptake, futhi ngaleyo ndlela ibe nomphumela we-antidepressant, kuyilapho futhi inomthelela ovimbelayo ebuhlungu obuphakathi.Isici sayo sesayensi yezokwelapha siyakwazi ukuvimbela ukuphinda kuthathwe ulwelwesi lwe-neuronal pre-synaptic ku-5-hydroxy trptamine ne-norepinephrine kodwa esikhundleni salokho kube nomthelela ophansi wokuvinjelwa ekuthathweni kabusha kwe-dopamine.I-Duloxetine hydrochloride ikhonjiswe ekucindezelekeni futhi iyasebenza ekwelapheni kokubili ukucindezeleka okungapheli kanye nokungapheleli kanye nomuzwa wobuhlungu obuhambisana nokucindezeleka.Inomthamo wokwelapha ongu-60mg/d~120mg/d ngokuvikeleka okuhle kanye nokusabela okungekuhle okumbalwa okunokusabela okungekuhle okuvamile njengokucanuzela kwenhliziyo, umlomo owomile, ukuqunjelwa, ukungakuthandi ukudla, ukukhathala, ukozela, nokukhuphuka kokujuluka.Esinye isibonakaliso ubuhlungu obubangelwa i-diabetesic neuropathy.