I-Candesartan CAS:139481-59-7 Isithombe Esifakiwe Somhlinzeki Womkhiqizi

Candesartan CAS:139481-59-7 Umkhiqizi Supplier

I-Candesartan iyimphikisi ye-angiotensin II receptor I (AT1), i-IC50s=1.12 kanye ne-2.86 nM ye-bovine adrenal cortex kanye ne-aorta kanogwaja ngokulandelanayo. Ngokukhetha ivimbela ukufinyela okubangelwa i-angiotensin II kwama-aortic anogwaja angenawo umthelela ekufinyezweni kwe-nodpiine , KCl, serotonin, PGF2αnoma endothelin.

Oda noma Cela I-Quote

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isicelo kanye Nomphumela

I-Candesartan iyisitha esikhethiwe se-AT1 (i-angiotensin II receptor 1).Ukuphikisana kwama-angiotensin receptors kuvimbela i-vasoconstriction kanye nokukhiqizwa kwe-aldosterone, okuholela ekwehleni kwamanzi kanye nokuhlushwa kwe-sodium ku-plasma yegazi.Ibonisa imiphumela ye-antihypertensive kumamodeli ezilwane.Isetshenziswa ekwelapheni ukwehluleka kwenhliziyo, njenge-antihypertensive.I-Candesartan ayithinti ukusebenza kweseli noma ukwanda kodwa inyusa ukubonakaliswa kwe-VEGF ne-interleukin-8 endaweni ekhulisiwe yamaseli e-KU-19-19.I-Candesartan (0.1 nM) inganciphisa impendulo enkulu yenkontileka ku-angiostensin II cishe ngama-50%.

Isampula Lomkhiqizo

Ukupakishwa komkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	I-C24H20N6O3
Isivivinyo	99%
Ukubukeka	Impushana emhlophe
Inombolo ye-CAS.	139481-59-7
Ukupakisha	1KG 25KG
I-Shelf Life	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	ISO.