I-Bz-Glu-OH CAS: 6094-36-6

I-Bz-Glu-OH idlala indima ebalulekile ekwakhiweni kwama-peptide, isebenza njengesisekelo esibalulekile sokwakha ama-peptide anezici ezithile zesakhiwo nokusebenza. Ukuba khona kweqembu le-benzyl ester kuthuthukisa ukusebenzisana kwe-hydrophobic kanye nokuqina kwe-peptide, okwenza kube wusizo ekudaleni ama-peptide anezakhiwo ezilungiselelwe njengokuthuthukiswa kokungena kwe-membrane noma ukucaciswa kwethagethi. Ekuthuthukisweni kwemithi, le nhlanganisela isetshenziselwa ukudala izidakamizwa ezisekelwe kuma-peptide ezinokuqina okuthuthukisiwe kanye nokutholakala kwezinto eziphilayo, okungenzeka kuholele emiphumeleni yokwelapha ethuthukisiwe. Ngaphezu kwalokho, ocwaningweni lwe-proteomics kanye nolwe-biochemical, i-Bz-Glu-OH ingasetshenziswa ukutadisha ukusebenzisana kwama-protein nama-protein, ukuphenya umsebenzi we-enzymatic, kanye nokuhlola ukuguquguquka kokugoqwa kwama-protein. Isakhiwo sayo esilungiselelwe sivumela abacwaningi ukuthi bahlole ubunzima bezinqubo zamaseli kanye nezindlela zezifo, okufaka isandla ekuthuthukisweni kokuqonda impilo kanye ne-pathology. Ukuguquguquka kanye nokuhambisana kwenhlanganisela nezimo ezahlukahlukene zokuhlola kwenza kube yingxenye ebalulekile yokucacisa ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Ngamafuphi, i-Bz-Glu-OH imele ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide anezakhiwo ezithile futhi ihlukanise izindlela eziyisisekelo zezinqubo zezinto eziphilayo, ngaleyo ndlela inikele ekuthuthukisweni kwezokwelapha kanye ne-biotechnology.