I-Boc-MeNle-OH CAS:117903-25-0

I-Boc-MeNle-OH isetshenziswa kakhulu ekuhlanganisweni kwe-peptide yesigaba esiqinile ukudala ama-peptide aklanywe ngokwezifiso anezinhlu ezithile kanye nokusebenza. Njengendlela evikelwe ye-N-methyl-norleucine, ivumela ukufakwa okulawulwayo kwezinsalela ze-N-methyl-norleucine kuchungechunge lwe-peptide olukhulayo, ivimbela ukusabela okungathandeki okungathandeki futhi ivumele ukuhlanganiswa kwama-peptide ayinkimbinkimbi anezakhiwo ezilungiselelwe. Ku-bioconjugation kanye ne-chemistry biology, i-Boc-MeNle-OH isebenza njengesakhiwo esiguquguqukayo sokudala ama-peptide asebenzayo, ama-probe anelebula, kanye nezindlela zokwelapha ezisekelwe ku-peptide. Ukusetshenziswa kwayo kwenza ukuguqulwa okunembile kwama-peptide namaprotheni, kusiza ukuthuthukiswa kwama-molecule asebenzayo amaningi ngokuqina okuthuthukisiwe, ukucaciswa okuqondiwe, noma amakhono okuthwebula izithombe zezinhlelo zokusebenza ezahlukahlukene ze-biomedical. Ngaphezu kwalokho, ekutholakaleni kwemithi kanye nokuthuthukiswa kokwelapha, i-Boc-MeNle-OH isetshenziswa ukudala ama-peptide conjugates nama-peptide aguquliwe anamaphrofayili e-pharmacokinetic athuthukisiwe kanye nemisebenzi ye-biological. Lezi zinguquko zingathuthukisa ukusebenza kahle, ukukhetha, kanye nokulethwa kwemithi esekwe ku-peptide, okunegalelo ekuthuthukisweni kwemithi enembile kanye nezindlela zokwelapha eziqondiwe. Sekukonke, ukuthembeka kanye nokuguquguquka kwe-Boc-MeNle-OH ekuhlanganisweni kwe-peptide kanye ne-bioconjugation kwenza kube ithuluzi elibalulekile lokuthuthukisa ucwaningo ekutholakaleni kwezidakamizwa, i-chemistry biology, kanye ne-proteomics, okunikeza amathuba ahlukahlukene okuthuthukisa izinhlelo zokusebenza ezintsha ze-biomedical.