I-Boc-Leu-ONp CAS:3350-19-4

I-Boc-Leu-ONp isetshenziswa kabanzi emasu okuhlanganisa i-bio kanye nezinqubo zokuguqula i-peptide. Ekuhlanganisweni kwe-peptide, ivumela ukufakwa okulawulwayo kwezinsalela ze-leucine kuchungechunge lwe-peptide, okuvumela ukunamathiswa okuqondiwe kwamaqembu ahlukahlukene asebenzayo, amalebula, noma ama-molecule ukuze kusetshenziswe ngezindlela ezahlukahlukene. Lokhu kuguqulwa okukhethiwe kusiza ekudalweni kwama-peptide asebenzayo amaningi anezakhiwo ezilungiselelwe, njengokuqina okuthuthukisiwe, ukucaciswa okuqondiwe, noma amakhono okuthwebula izithombe. Ocwaningweni lwe-proteomics, i-Boc-Leu-ONp ivumela ukulebula kwamaprotheni nama-peptide endaweni ethile, okufaka isandla ekuhlaziyweni kwesakhiwo, izifundo zokusebenzisana, kanye nokuhlolwa okusekelwe ku-mass spectrometry. Ukunamathiswa okulawulwayo kwe-Boc-Leu-ONp ezinsalela ze-leucine kwenza ukuhlukaniswa okunembile kanye nokuhlaziywa kokusebenza kwamaprotheni nama-peptide, kusekela intuthuko ekuqondeni izinhlelo zebhayoloji kanye nezinqubo zesifo. Ngaphezu kwalokho, ekuthuthukisweni kwemithi, i-Boc-Leu-ONp idlala indima ebalulekile ekuhlanganiseni ama-ejenti okwelapha kuma-peptide noma amaprotheni, ukudala izinhlelo zokulethwa kwemithi eziqondiwe, ama-conjugates ezidakamizwa ezilwa namagciwane, noma izakhiwo zokugoma ezinephrofayili ye-pharmacokinetic ethuthukisiwe kanye nemiphumela encishisiwe engaqondiwe. Ngamafuphi, ukuthembeka kanye nokuguquguquka kwe-Boc-Leu-ONp ekuguqulweni kwe-peptide kanye ne-bioconjugation kwenza kube ithuluzi elibalulekile lokuthuthukisa ucwaningo ekutholakaleni kwezidakamizwa, i-chemistry biology, kanye ne-proteomics, okunikeza amathuba ahlukahlukene okuthuthukisa izinhlelo zokusebenza ezintsha ze-biomedical.