I-Boc-D-Phe-ONp CAS:16195-70-9

I-Boc-D-Phe-ONp idlala indima ebalulekile ekwakhiweni kwe-peptide, ikakhulukazi ekwakhiweni kwe-peptide yesigaba esiqinile (i-SPPS) kanye nokwakhiwa kwe-peptide yesigaba sesisombululo. Njenge-amino acid derivative evikelwe, yenza kube lula ukufakwa kwezinsalela ze-D-phenylalanine ku-peptide sequences. Ku-SPPS, i-Boc-D-Phe-ONp isetshenziselwa ukwethula ngokukhetha amayunithi e-D-phenylalanine ngesikhathi sokuhlanganiswa kwe-peptide chain ezisekelweni eziqinile, kuyilapho ekwakhiweni kwe-solution-phase, ivumela ukwakheka kwezibopho ze-peptide ekuphenduleni okusekelwe kwisisombululo. Abacwaningi nososayensi bemithi basebenzisa i-Boc-D-Phe-ONp ukudala ama-peptide aklanyelwe nge-D-amino acid sequences ethize elungiselelwe ukuhlolwa kwezinto eziphilayo, izifundo zesakhiwo, kanye nokuthuthukiswa kwemithi. Besebenzisa i-reactivity yeqembu le-4-nitrophenyl ester, bangafinyelela ukuhlangana okuphumelelayo namaqembu ama-amino, okuholela ekwandiseni okulawulwayo kwamaketanga e-peptide kanye nokukhiqizwa kwezakhiwo ze-peptide ezahlukahlukene. Ukuguquguquka kwe-Boc-D-Phe-ONp kuyenza ibe ithuluzi eliyigugu emikhakheni eyahlukahlukene njenge-biochemistry, i-pharmacology, kanye ne-biotechnology. Ukuhambisana kwayo nezinqubo ezijwayelekile zokwenziwa kwe-peptide, isivuno esikhulu, kanye nokusebenza okuthembekile kunegalelo ekusetshenzisweni kwayo kabanzi ezindaweni zezemfundo nezezimboni. Kungakhathaliseki ukuthi isetshenziswa ocwaningweni oluyisisekelo noma emizamweni yokuthola izidakamizwa, i-Boc-D-Phe-ONp yenza kube lula ukudalwa kwama-peptide asekela intuthuko ebalulekile kwisayensi yezokwelapha kanye nokusungula izinto ezintsha kwezokwelapha.