I-5′-O-Tritylthymidine CAS: 7791-71-1 Intengo Yomkhiqizi

I-5′-O-Tritylthymidine iyi-derivative ye-thymidine, okuyi-nucleoside eyakhiwe yi-pyrimidine base thymine exhunywe kushukela we-deoxyribose. Iqembu le-trityl liyiqembu elivikelayo elivame ukusetshenziswa ekwakhiweni kwezinto eziphilayo ukufihla okwesikhashana iqembu elisebenzayo elisebenzayo. Endabeni ye-5′-O-Tritylthymidine, iqembu le-trityl linamathele eqenjini le-5′ hydroxyl likashukela we-deoxyribose we-thymidine. Lokhu kuguqulwa kuvame ukusetshenziswa ekwakhiweni nasekuguqulweni kwama-nucleic acid, ikakhulukazi kumongo wokwenziwa kwe-DNA yesigaba esiqinile. Iqembu le-trityl lisebenza ukuvikela iqembu le-5′ hydroxyl ngesikhathi sokuphendula kwamakhemikhali futhi lingasuswa ngokukhetha ngaphansi kwezimo ezithambile ukuze kukhiqizwe iqembu le-hydroxyl yamahhala ukuze kwenziwe okulandelayo. Le nhlanganisela ithola ukusetshenziswa emkhakheni we-nucleic acid chemistry kanye nokwakheka kwe-oligonucleotide.