2,2,2-TRIFLUOROETHYL I-TRIFLUOROACETATE CAS:407-38-5

I-2,2,2-Trifluoroethyl trifluoroacetate (TFETA) iyinhlanganisela eguquguqukayo enezakhiwo zamakhemikhali ezihlukile ezifaka isandla ekusebenzeni kwayo okubanzi ezisetshenziswayo ezimbonini ezahlukahlukene. Izakhiwo I-TFETA ibonakaliswa yisakhiwo sayo sama-molecule, esineqembu le-trifluoroethyl (-CF3CH2-) elinamathiselwe ku-ester ye-trifluoroacetate (-OC(O)CF3). Lokhu kuhlanganiswa kuphumela kuketshezi olucacile, olungenambala olunephuzu eliphezulu lokubila, cishe i-145°C, kanye nokuncibilika okuhle kakhulu ezinyibilikisini eziphilayo. Inhlanganisela ikhombisa ukusabela okuphansi ngenxa yemvelo yokuhoxiswa kwama-athomu e-fluorine ngama-electron, okunikeza ukuzinza kwamakhemikhali okuqinile ngaphansi kwezimo ezahlukahlukene. Izakhiwo ze-TFETA ziyenza ifaneleke ezinhlelweni ezidinga ukungasebenzi kahle, njengokwenziwa kwezinto ezizinzile kanye nezingubo zokuvikela. Ukusetshenziswa Kwe-Organic Synthesis: I-TFETA isebenza njenge-intermediate ebalulekile ekuhlanganisweni kwezinto eziphilayo, lapho ihlanganyela khona ekuphenduleni ukuze ingenise ukusebenza kwe-fluorinated kuma-molecule ayinkimbinkimbi. Leli khono libaluleke kakhulu kumakhemikhali emithi ekudaleni izidakamizwa ze-fluorinated kanye nasekukhiqizweni kwamakhemikhali akhethekile lapho kudingeka khona ukuzinza okuthuthukisiwe kanye nokumelana kwamakhemikhali. Isayensi Yezinto Ezisetshenziswayo: Ukuqina kwamakhemikhali kanye nokuncibilika kwe-TFETA kwenza kube yingxenye efanelekile ekwakhiweni kwezimbozo nezinto ezidinga ukusebenza okuthile. Isetshenziselwa ukuthuthukisa ukuqina kanye nezakhiwo zokuvikela zezindawo ekuwohlokeni kwemvelo kanye nokuhlaselwa ngamakhemikhali, okufaka isandla ebude besikhathi sezinto ezisetshenziswayo kusukela ekumbozweni kwezimoto kuya ezingxenyeni ze-elekthronikhi. Izicelo Zemithi: Indima ye-TFETA ekuhlanganisweni kwezinto eziphilayo ifinyelela ekusetshenzisweni kwemithi, lapho isakhiwo sayo esifakwe i-fluorinated singaguqula khona umsebenzi wezinto eziphilayo kanye nezakhiwo ze-pharmacokinetic zama-molecule emithi. Lokhu kuyenza ibe ithuluzi elibalulekile ekutholakaleni kwemithi kanye nezinqubo zokuthuthukiswa okuhloswe ukuthuthukisa ukusebenza kahle kokwelapha kanye nokutholakala kwezinto eziphilayo. Ukwenziwa kwe-TFETA kwenziwa ngokwenziwa kwe-trifluoroacetic acid (CF3COOH) nge-2,2,2-trifluoroethanol (CF3CH2OH) ngaphansi kwezimo ze-asidi. Ukusabela kukhiqiza i-TFETA kanye namanzi njengomkhiqizo olandelanayo, ongahlanzwa nge-distillation noma i-solvent extraction ukuze kutholakale ubumsulwa obuphezulu obufanele ukusetshenziswa kwezimboni. Ukwenziwa okulula kanye nokuphathwa kwe-TFETA kunegalelo ekusebenzeni kwayo kahle kwezindleko kanye nokusetshenziswa kabanzi emikhakheni ehlukahlukene edinga ama-compounds afakwe i-fluorinated. Ngamafuphi, i-2,2,2-trifluoroacetate ye-trifluoroacetate iyinhlanganisela eguquguqukayo ebalulekile ekuhlanganisweni kwezinto eziphilayo, isayensi yezinto, kanye ne-chemistry yezokwelapha. Izakhiwo zayo zamakhemikhali ezihlukile zivumela ukuthuthukiswa kwezinto ezithuthukisiwe kanye nemithi enokuqina okuthuthukisiwe kanye nezici zokusebenza, okugcizelela ukubaluleka kwayo ezisetshenziswayo zezimboni zanamuhla.