I-β-Nicotinamide Mononucleotide CAS:1094-61-7

I-β-Nicotinamide mononucleotide (NMN) isetshenziselwa ukutadisha ama-motifs abophayo ngaphakathi kwama-aptamers e-RNA kanye nezinqubo zokwenza kusebenze i-ribozyme ezihlanganisa izingcezu ze-RNA ezicushiwe ze-β-nicotinamide mononucleotide (β-NMN).I-NMN iyinucleotide etholakala ku-ribose ne-nicotinamide.I-Niacinamide (i-nicotinamide,) iphuma kuvithamini B3, owaziwa nangokuthi i-niacin.) Njengesandulela samakhemikhali ezinto eziphilayo we-NAD+, ingase ibe usizo ekuvimbeleni i-pellagra.
I-β-Nicotinamide mononucleotide iyingxenye emaphakathi ku-biosynthesis ye-nicotinamide adenine dinucleotide (NAD+).I-Nicotinamide phosphoribosyltransferase (Nampt) igqugquzela ukujiya kwe-nicotinamide nge-5-phosphoribosyl-1-pyrophosphate ukuze ikhiqize i-β-NMN, kamuva eguqulelwa ku-NAD+ nge-β-NMN adenyltransferase. I-NAD biosynthesis kanye nokukhishwa kwe-insulin evuselelwe i-glucose kumodeli yegundane ye-Nampt+/- yesifo se-metabolic, ebonisa indima ye-Namp ekusebenzeni kweseli ye-β.