I-Z-MeLeu-OH CAS:33099-08-0

Ukukhuthazwa kokukhula: I-L-Arginine yaziwa ngokukhuthaza ukukhishwa kwama-hormone okukhula ezilwaneni, okungadala izinkinga

Abacwaningi bavame ukusebenzisa i-Z-MeLeu-OH kumakhemikhali e-peptide ukuze kuguqulwe ama-peptide endaweni ethile. Ngokufaka i-Z-MeLeu-OH ku-peptide sequences, ososayensi bangangenisa i-methylated leucine residue, okuvumela ukutadisha imiphumela ye-methylation esakhiweni se-peptide, ukuzinza, kanye nokusebenzisana namanye ama-molecule. Ngaphezu kwalokho, i-Z-MeLeu-OH ingasetshenziswa njengebhloko yokwakha ukuhlanganiswa kwama-peptide aguquliwe anemisebenzi ethile noma izakhiwo, okwandisa ububanzi bocwaningo olusekelwe kuma-peptide kanye nezicelo ekutholakaleni kwezidakamizwa, ama-proteomics, kanye ne-chemistry biology. Ukuhambisana kwayo nezinqubo ezijwayelekile zokwenziwa kwama-peptide kanye namasu okuhlanganisa i-bio kwenza i-Z-MeLeu-OH ibe yi-reagent ebalulekile kubacwaningi abafuna ukulawula nokutadisha izakhiwo nemisebenzi yama-peptide ngokunemba.

Inikeza inhlonipho ekukhuleni nasekuthuthukisweni okuthuthukisiwe. Ikhuthaza ukwakheka kwamaprotheni, okubalulekile ekukhuleni kwemisipha, futhi kungathuthukisa ukutholakala kwesisindo somzimba ezilwaneni.

Ukukhiqizwa kwe-nitric oxide: I-L-Arginine iyisandulela sokwenziwa kwe-nitric oxide (NO) emzimbeni. I-nitric oxide ihilelekile ezinqubweni ezahlukene zomzimba, okuhlanganisa ukwanda kwemithambo yegazi, ukusebenza komzimba, kanye nokusabalalisa amaseli. Ukwengeza i-L-Arginine ekudleni kwezilwane kungathuthukisa ukukhiqizwa kwe-NO, okuholela ekuthuthukisweni kokugeleza kwegazi, impendulo yomzimba, kanye nokumuncwa kwezakhamzimba.

Umsebenzi Wokuzivikela Emzimbeni: I-L-Arginine idlala indima ebalulekile ekusekeleni isimiso somzimba sokuzivikela. Ihilelekile ekukhiqizweni kwamangqamuzana omzimba, njenge-T-cells nama-macrophage, kanye nama-antibodies. Ngokuhlinzeka ngokuhlinzekwa okwanele kwe-L-Arginine ekudleni kwezilwane, umsebenzi wokuzivikela emzimbeni ungathuthukiswa, okuholela ekuthuthukisweni kokumelana nezifo kanye nempilo iyonke.

Ukusebenza kokuzala: I-L-Arginine ibalulekile ezinqubweni zokuzala ezilwaneni. Ihilelekile ekukhiqizweni kwesidoda kanye nokuhamba kwabesilisa futhi ingathuthukisa ukuzala. Kwabesifazane, i-L-Arginine isekela ukuthuthukiswa kanye nokusebenza kwesibeletho kanye ne-placenta, ithuthukisa ukusebenza kokuzala kanye nokwandisa usayizi wesilwane.

Ukuphathwa kokucindezeleka: I-L-Arginine iboniswe ukuthi inomthelela omuhle ekusabeleni kokucindezeleka kwezilwane. Inganciphisa amazinga e-cortisol abangelwa ukucindezeleka futhi ikhuthaze isimo sokuphumula. Ngokufaka i-L-Arginine ekudleni kwezilwane, ukubekezelela ukucindezeleka kanye nenhlalakahle iyonke kungathuthukiswa.