I-ZD-Arg(NO2)-OH CAS:2279-08-5

I-ZD-Arg(NO2)-OH idlala indima ebalulekile ekwakhiweni kwe-peptide ngokuvumela ukufakwa kwe-D-arginine derivatives kanye nokuguqulwa kweqembu le-nitro ku-peptide sequences. Lawa ma-peptide aguquliwe anikeza amathuba ahlukile okuphenya ubudlelwano besakhiwo nomsebenzi, ukufunda ukuguqulwa kwangemva kokuhumusha, kanye nokuhlola umthelela wokuguqulwa okuthile kwe-stereochemical kanye namakhemikhali emsebenzini we-peptide kanye nokusebenza kwe-bioactivity. Ngaphezu kwalokho, i-ZD-Arg(NO2)-OH inegalelo ekuthuthukisweni kwamakhemikhali asekelwe ku-peptide ukuze kusetshenziswe izindlela zokwelapha ezingaba khona, isebenzisa izakhiwo ezihlukile zama-D-amino acid ekwakhiweni kwe-peptide. Ngaphezu kwalokho, le nhlanganisela isetshenziswa kakhulu ekutadisheni ukusebenzisana kwamaprotheni nama-protein, umsebenzi we-enzymatic, kanye nemicimbi yokubopha i-receptor-ligand, ikakhulukazi igxile ethonyeni lezinsalela ze-D-amino acid eziqukethe iqembu le-nitro ezindleleni zezinto eziphilayo kanye nezinqubo zokuqashelwa kwama-molecule. Ukusetshenziswa kwayo kudlulela ekudalweni kwama-peptide angokwezifiso ngokuguqulwa okwenziwe ngokwezifiso kwezicelo ekuthuthukisweni kwemithi, ukuhlolwa kwamakhemikhali, kanye nezifundo zebhayoloji yesakhiwo. Ngamafuphi, ukuguquguquka kanye nokuhambisana kwe-ZD-Arg(NO2)-OH nezindlela ezahlukahlukene zokwenziwa kwenza kube yingxenye ebalulekile kososayensi nabacwaningi abangochwepheshe be-peptide kanye ne-organic chemistry, okubanikeza ithuluzi elinamandla lokuhlola umthelela wokuguqulwa kwe-stereochemical kanye namakhemikhali ekuziphatheni kwe-peptide kanye nomsebenzi webhayoloji, ngaleyo ndlela kunegalelo ekuthuthukisweni kokutholakala kwezidakamizwa, i-chemical biology, kanye nocwaningo lwezokwelapha.