I-Z-Arg(NO2)-OH CAS:2304-98-5

I-Z-Arg(NO2)-OH isebenza njengengxenye ebalulekile ekuguqulweni kwesu kwama-peptide namaprotheni, ikakhulukazi ezifundweni ezihilela ukuguqulwa kwangemva kokuhumusha noma uphenyo lobudlelwano besakhiwo nomsebenzi. Ukwethulwa kweqembu le-nitro kwenza kube lula ukulungisa izakhiwo ze-peptide, okuthonya umsebenzi wezinto eziphilayo kanye nokusebenzisana kwama-molecule. Ngaphezu kwalokho, leli khemikhali lisetshenziswa ekuhloleni umthelela wokuguqulwa okuthile ezinqubweni ze-enzymatic, ukusebenzisana kwe-receptor-ligand, kanye nezinye izimo ze-biochemical. Ngaphezu kwalokho, i-Z-Arg(NO2)-OH ithola ukusetshenziswa ekwakheni ama-inhibitors asekelwe ku-peptide, ekuqondiseni ama-enzyme noma ama-receptor athile, kanye nasekuthuthukiseni ama-peptide derivatives anezimpawu ze-physicochemical ezishintshiwe. Ukusetshenziswa kwayo kudlulela ekuphenyeni indima yama-peptide aqukethe iqembu le-nitro ekuguquleni izindlela zezinto eziphilayo, enezela ubukhulu obubalulekile ekutholakaleni kwezidakamizwa kanye nezifundo zebhayoloji yesakhiwo. Abacwaningi basebenzisa ne-Z-Arg(NO2)-OH ukudala ama-peptide enziwe ngokwezifiso ezinhlobonhlobo zezicelo, kufaka phakathi ukuhlola imiphumela yokuguqulwa okuqondiwe emsebenzini we-peptide, ukuzinza, kanye nokumuncwa kwamaseli. Ngamafuphi, imvelo ye-Z-Arg(NO2)-OH eguquguqukayo kanye nokuhambisana kwayo nezindlela ezahlukahlukene zokwenziwa kwenza kube ithuluzi elibalulekile kososayensi nabacwaningi ababandakanyeka kumakhemikhali e-peptide kanye ne-organic, okubanika amandla okuhlola izinguquko ezenziwe ngokwezifiso kanye nomthelela wazo ekuziphatheni kwe-peptide, okuvula indlela yokuthuthuka ekuthuthukisweni kwemithi, ucwaningo lwe-biochemical, kanye nezicelo ze-biomedical.