I-Z-Ala-ONp CAS:1168-87-2

I-Z-Ala-ONp isebenza njenge-reagent ebalulekile ekwakhiweni kwe-peptide, ikakhulukazi ekuguqulweni okukhethiwe kwama-peptide namaprotheni. Ukusebenza kwe-ONp ester kwenza kube lula ukwethulwa kwezinsalela ze-alanine ezindaweni ezithile ngaphakathi kochungechunge lwe-peptide ngokusabela nama-amine, okuvumela ukulungiswa okunembile kwezakhiwo ze-peptide. Ngaphezu kwalokho, i-Z-Ala-ONp isetshenziswa kakhulu kumasu okuhlanganisa i-bio okuthuthukisa ama-conjugates e-protein-peptide, ama-enzyme inhibitors asekelwe ku-peptide, kanye nezinye izinto ezisetshenziswayo ze-peptide. Ngaphezu kwalokho, le nhlanganisela isetshenziswa ocwaningweni lokusabela kwe-enzyme, ukusebenzisana kwe-receptor-ligand, kanye nemicimbi yokubopha i-peptide-protein. Ukuhambisana kwayo nezindlela ezahlukahlukene zokwenziwa kwenza abacwaningi bakwazi ukudala ama-peptide ngokwezifiso zokusetshenziswa ekuthuthukisweni kwemithi, ukuhlolwa kwe-biochemical, kanye nezifundo ze-biology yesakhiwo. Ngaphezu kwalokho, indima ye-Z-Ala-ONp ifinyelela ekuthuthukisweni kwezinto eziphilayo ezisekelwe ku-peptide kanye nama-bioconjugates ezicelo ze-biomedical kanye ne-biotechnological. Ngamafuphi, i-Z-Ala-ONp idlala indima ebalulekile ekuthuthukisweni kwe-peptide chemistry kanye nocwaningo lwe-bioconjugation, inika amandla ososayensi nabacwaningi ukuthuthukisa ama-peptide derivatives nama-conjugates amasha ngezinhlelo zokusebenza ezingaba khona zokwelapha, zokuxilonga, kanye nocwaningo.