I-Tritylcandesartancilexetil CAS:170791-09-0

I-Tritylcandesartan cilexetil, eyaziwa nangokuthi i-tritylcandesartan cilexetil, umuthi wezokwelapha osetshenziswa kakhulu ekwelapheni umfutho wegazi ophakeme (umfutho wegazi ophezulu). Iyingxenye yemithi eyaziwa ngokuthi ama-angiotensin II receptor blockers (ama-ARB). Le mithi isebenza ngokuvimbela isenzo se-angiotensin II, into emzimbeni engabangela ukuba imithambo yegazi inciphe, ngaleyo ndlela yandise umfutho wegazi. Ngokuvimbela le ndlela, i-tritylcandesartan cilexetil isiza ukuphumula nokwandisa imithambo yegazi, okuholela ekwehleni kwamazinga omfutho wegazi. Ngaphezu kwendima yayo ekuphatheni umfutho wegazi ophakeme, i-tritylcandesartan cilexetil inganikezwa futhi ukuvikela izinso ekulimaleni ngenxa yesifo sikashukela, ikakhulukazi ezigulini ezinesifo sikashukela sohlobo 2 kanye nomfutho wegazi ophakeme. Lo muthi uboniswe ukuthi unciphisa ingozi yokuqhubeka kwesifo sezinso kulaba bantu, okwenza kube inketho ebalulekile kulabo bantu. Ngaphezu kwalokho, i-tritylcandesartan cilexetil ingaba yingxenye yohlelo lokwelapha oluphelele lokwehluleka kwenhliziyo. Kungase kunikezwe ukuze kuthuthukiswe izimpawu, kuncishiswe ukulaliswa esibhedlela okuhlobene nokwehluleka kwenhliziyo, futhi kuthuthukiswe ikhwalithi yokuphila iyonke kubantu abaphila nalesi simo. Kubalulekile ukuqaphela ukuthi ukusetshenziswa kwe-tritylcandesartan cilexetil kufanele kunqunywe uchwepheshe wezempilo, futhi iziguli kufanele zilandele ngokuqinile umthamo onqunyiwe kanye nemiyalelo yokuphathwa enikezwa umhlinzeki wazo wezempilo. Ngaphezu kwalokho, imiphumela emibi engaba khona kanye nokusebenzisana kwezidakamizwa kufanele kucatshangelwe ngokucophelela lapho kusetshenziswa lo muthi. Iziguli zelulekwa ukuthi zixhumane nomhlinzeki wazo wezempilo ukuze zithole isiqondiso esiqondene nomuntu siqu mayelana nokusetshenziswa kwe-tritylcandesartan cilexetil.