I-Reductase, i-glutathione CAS:9001-48-3

I-Glutathione reductase iyi-enzyme edlala indima ebalulekile ekugcineni ibhalansi ye-glutathione encishisiwe ne-oxidized (GSH/GSSG) emaseli. I-Glutathione iyi-tripeptide eyakhiwe ama-amino acid i-glycine, i-cysteine, ne-glutamate. Isebenza njenge-antioxidant enkulu yamaseli futhi ihilelekile ezinqubweni ezahlukahlukene zamaseli, okuhlanganisa ukukhishwa kwe-detox emzimbeni, ukwakheka nokulungiswa kwe-DNA, kanye nokwakheka kwamaprotheni.

I-Glutathione reductase ikhuthaza ukwehla kwe-glutathione e-oxidized (GSSG) ibe yifomu layo elincishisiwe (GSH) ngokusebenzisa i-NADPH (nicotinamide adenine dinucleotide phosphate) njenge-cofactor. Lokhu kusabela kubalulekile ekugcineni isimo esincishisiwe se-glutathione emaseli, njengoba i-GSSG inganqwabelana lapho kukhona ukucindezeleka kwe-oxidative.

Ngokugcina isilinganiso esifanele se-GSH ku-GSSG, i-glutathione reductase isiza ukuvikela amaseli ekulimaleni kwe-oxidative okubangelwa izinhlobo ze-oxygen (ROS) ezisabelayo kanye namanye ama-molecule ayingozi. Isebenza njengomdlali obalulekile ohlelweni lokuvikela amaseli olune-antioxidant.

Ngaphezu kwalokho, i-glutathione reductase ibandakanyeka ekuvuseleleni i-glutathione disulfide (GSSG) ekhiqizwa ngesikhathi sezinqubo ezahlukahlukene ze-metabolic, okuqinisekisa ukutholakala kwe-glutathione encishisiwe (GSH) yemisebenzi yayo eminingi yamaseli.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

Ukulawulwa kwe-Redox: I-Glutathione reductase idlala indima ebalulekile ekugcineni ibhalansi ye-redox yeselula. Isiza ukugcina isilinganiso esifanele se-glutathione encishisiwe (GSH) kuya ku-glutathione e-oxidized (GSSG) ngokuguqula i-GSSG ibe yi-GSH. Lokhu kulinganisela kwe-redox kubalulekile ezinqubweni eziningi zamaseli futhi kubalulekile ekusindeni nasekusebenzeni kwamaseli.

Ukuvikela i-Antioxidant: I-Glutathione reductase, ngokugcina amazinga e-glutathione ancishisiwe, ithuthukisa indlela yokuvikela i-antioxidant yamaseli. I-Glutathione isebenza njenge-antioxidant enamandla, isusa izinhlobo ze-oxygen ezisebenzayo (ROS) kanye nezinye izinto eziyingozi ezingabangela umonakalo wamaseli kanye nokucindezeleka kwe-oxidative.

Ukususa Ubuthi: I-Glutathione reductase ihilelekile ekususeni ubuthi ezingxubeni eziyingozi kanye nama-xenobiotic. Isiza ekuhlanganiseni izinto ezinobuthi ne-glutathione, okuholela ekususweni kwazo emzimbeni.

Umsebenzi wesistimu yokuzivikela komzimba: I-Glutathione reductase idlala indima ebalulekile ekusebenzeni kwesistimu yokuzivikela komzimba. Isiza ukugcina isimo se-redox samaseli omzimba, ivuselela kahle izimpendulo zomzimba, futhi isekela ukwanda nokwehlukaniswa kwamaseli omzimba.

Uphawu lokuxilonga kanye nokubikezela: Umsebenzi we-Glutathione reductase ungalinganiswa ukuze kuhlolwe isimo se-redox kanye namazinga okucindezeleka kwe-oxidative ezifweni ezahlukene. Izinguquko emsebenzini we-glutathione reductase zingasebenza njengezimpawu zokuxilonga kanye nokubikezela izimo ezahlukene, okuhlanganisa umdlavuza, izifo zenhliziyo, izifo zesibindi, kanye nezinkinga ze-neurodegenerative.

Izicelo zokwelapha: I-Glutathione reductase iyindlela engaba khona yokungenelela kokwelapha. Ukushintsha umsebenzi noma ukubonakaliswa kwayo kungahlolwa njengesu lokwelapha lokulwa nezifo ezihlobene nokucindezeleka kwe-oxidative, njengezinkinga ze-neurodegenerative, izifo zenhliziyo, kanye nomdlavuza othile.

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	I-NA
Ukuhlolwa	99%
Ukubukeka	Uketshezi oluphuzi
Inombolo ye-CAS	9001-48-3
Ukupakisha	Encane futhi enkulu
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.