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I-Methyl 2-aminonicotinate CAS:14667-47-1
I-Methyl 2-aminonicotinate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C7H8N2O2. Iyi-methyl ester ye-2-aminonicotinic acid, ebonakala ngeqembu lama-amino endaweni yesibili yendandatho ye-pyridine kanye neqembu le-methoxycarbonyl (-COOCH3). Lesi sakhiwo sinikeza izakhiwo zamakhemikhali ezihlukile kanye nemisebenzi engaba khona yezinto eziphilayo. Ucwaningo lubonisa ukuthi i-methyl 2-aminonicotinate ingaba nezicelo kumakhemikhali ezokwelapha, kufaka phakathi imiphumela yokulwa namagciwane kanye nokulwa nokuvuvukala. Ukuguquguquka kwayo njengesihlanganisi sokwenziwa kwenza kube lula ukuthuthukiswa kwamakhemikhali e-bioactive ayinkimbinkimbi kakhulu, okwenza kube yinto ebalulekile yokuhlola okwengeziwe ekutholakaleni kwezidakamizwa kanye nokuhlanganiswa kwezinto eziphilayo.
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I-Hymecromone CAS:90-33-5
I-Hymecromone, eyaziwa nangokuthi i-4-methyllumbelliferone, iyinhlanganisela yokwenziwa enefomula yamakhemikhali i-C10H10O3. Ingowomndeni we-coumarin futhi ikhombisa izakhiwo ezahlukahlukene zemithi, okuhlanganisa nemiphumela yokulwa nokuvuvukala, i-antioxidant, kanye ne-antimicrobial. Ekuqaleni yayisetshenziswa njenge-ejenti yokuvikela isibindi, i-hymecromone ithole ukunakwa ocwaningweni ngenxa yokusetshenziswa kwayo okungenzeka kwezokwelapha ekwelapheni izifo zesibindi nezinye izimo zempilo. Ngaphezu kwalokho, ibonise ithemba ekuvimbeleni ama-enzyme athile ahlobene nokuqhubeka kwesimila, ngaleyo ndlela iyibeka njengomuntu ozongenela ucwaningo lomdlavuza. Iphrofayili yayo yokuphepha iyenza ibe yindaba ethakazelisayo kokubili ezindaweni zezokwelapha nezokuhlola.
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I-Ethyl 2-aminopyridine-3-carboxylate CAS:13362-26-0
I-Ethyl 2-aminopyridine-3-carboxylate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C9H10N2O2. Ifaka indandatho ye-pyridine ethathelwe indawo yiqembu lama-amino (-NH2) endaweni yesibili kanye ne-ethyl ester endaweni ye-carboxylic acid ku-carbon yesithathu. Lesi sakhiwo esiyingqayizivele sinikeza izakhiwo zamakhemikhali ezahlukahlukene kanye nemisebenzi engaba khona yezinto eziphilayo. Ucwaningo luphakamisa ukuthi i-ethyl 2-aminopyridine-3-carboxylate ingaba nezicelo kumakhemikhali ezokwelapha, kufaka phakathi imiphumela yokulwa namagciwane kanye nokulwa nokuvuvukala. Indima yayo njengesihlanganisi sokwenziwa iphinde isize ekudalweni kwamakhemikhali e-bioactive ayinkimbinkimbi kakhulu, okwenza kube yinto ebalulekile yokufunda kabanzi ekuthuthukisweni kwemithi.
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I-5-methyl tryptamine hydrochloride CAS:1010-95-3
I-5-Methyl tryptamine hydrochloride iyi-derivative ye-amino acid tryptophan eyenzeka ngokwemvelo, ehlukaniswe njengelungu lomndeni we-tryptamine. Le nhlanganisela ineqembu le-methyl endaweni yesihlanu yendandatho ye-indole futhi yaziwa ngezakhiwo zayo ezithinta ingqondo. Ucwaningo lukhombisile ukuthi ingathonya ama-serotonin receptors ebuchosheni, okungase kuthinte isimo sengqondo, ukuqonda, kanye nokuqonda. Ngenkathi izifundo zesayensi ku-5-methyl tryptamine zilinganiselwe, iyaziwa ngemiphumela yayo ku-neuroscience kanye ne-psychopharmacology. Iphrofayili yayo yokuphepha kanye namandla okwelapha ayaqhubeka nokuhlolwa ngaphakathi kwezimo ezahlukahlukene zokuhlola.
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I-5-Aminonicotinic acid CAS:24242-19-1
I-5-Aminonicotinic acid iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C6H6N2O2. Ivela ku-nicotinic acid, equkethe iqembu lama-amino (-NH2) endaweni yesihlanu yendandatho ye-pyridine. Lokhu kuguqulwa kwesakhiwo kunikeza izakhiwo zamakhemikhali ezihlukile kanye nemisebenzi engaba khona yezinto eziphilayo. Ucwaningo lubonisa ukuthi i-5-aminonicotinic acid ingabonisa imiphumela ehlukahlukene yezokwelapha, kufaka phakathi izakhiwo zokulwa nokuvuvukala, ukulwa namagciwane, kanye nokuvikela izinzwa. Indima yayo njengesisekelo sokwakha ekwakhiweni kwezinto eziphilayo iyenza ibe yigugu ekuthuthukiseni imithi emisha, ithuthukise ukubaluleka kwayo kumakhemikhali ezokwelapha futhi inikeze izindlela ezintsha zokuhlola ukwelashwa.
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I-Methyl 5-hydroxynicotinate CAS: 30766-22-4
I-Methyl 5-hydroxynicotinate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C7H7NO3. Ivela ku-nicotinic acid, equkethe iqembu le-hydroxyl endaweni yesihlanu kanye ne-methyl ester endaweni yokugcina i-carboxylic acid. Le nhlanganisela inesithakazelo kumakhemikhali emithi ngenxa yezinzuzo zayo zezempilo ezingaba khona, okuhlanganisa izakhiwo zokulwa nokuvuvukala kanye nezokudambisa ubuhlungu. Ucwaningo lukhombisile ukuthi i-methyl 5-hydroxynicotinate ingathonya izindlela ezahlukahlukene zezinto eziphilayo, okwenza kube yinto okufanele ihlolwe kabanzi ekuthuthukisweni kwemithi. Isakhiwo sayo esiyingqayizivele sivumela nezinhlelo zokusebenza ezahlukahlukene zokwenziwa, okuvule indlela yokudala ama-molecule ayinkimbinkimbi kakhulu kumakhemikhali emithi.
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I-5-Hydroxynicotinic acid CAS:27828-71-3
I-5-Hydroxynicotinic acid iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C6H6N2O3. Ivela ku-nicotinic acid, equkethe iqembu le-hydroxyl endaweni yesihlanu yendandatho ye-pyridine. Le nhlanganisela idale intshisekelo kumakhemikhali ezokwelapha kanye ne-pharmacology ngenxa yemisebenzi yayo engaba khona yezinto eziphilayo, okuhlanganisa izakhiwo zokulwa nokuvuvukala kanye nezokulwa namagciwane. Ucwaningo luphakamisa ukuthi i-5-hydroxynicotinic acid ingathonya izindlela ezahlukahlukene zokubonisa izimpawu, okwenza kube yinto okufanele ihlolwe kabanzi ekuthuthukisweni kwemithi. Ngaphezu kwalokho, isakhiwo sayo sivumela ukusetshenziswa okuhlukahlukene kokwenziwa, okungenzeka kusebenze njengesandulela sokwenziwa kwama-molecule ayinkimbinkimbi kakhulu e-bioactive.
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I-5-Bromo-2-hydroxyacetophenone CAS:1450-75-5
I-5-Bromo-2-hydroxyacetophenone iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C8H8BrO3. Iqukethe i-athomu ye-bromine kanye neqembu le-hydroxyl ezindaweni ezi-5 nezi-2, ngokulandelana, ze-acetophenone scaffold. Le nhlanganisela inesithakazelo ezicelweni ezahlukene zocwaningo lwamakhemikhali, ikakhulukazi ekuhlanganisweni kwezinto eziphilayo kanye ne-chemistry yezokwelapha. Amaqembu ayo ahlukile asebenzayo anika amandla okusebenza, okwenza ibe usizo njengomxhumanisi ekukhiqizweni kwemithi kanye namakhemikhali ezolimo. Ngaphezu kwalokho, ucwaningo ngomsebenzi wayo webhayoloji lubonise amandla ezakhiwo zokulwa namagciwane kanye nokulwa nomdlavuza, luqokomisa ukubaluleka kwayo ekuthuthukiseni ama-ejenti amasha okwelapha.
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I-PHENYL ACETATE CAS:122-79-2
I-Phenyl acetate iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali i-C8H8O2. Iyi-ester eyakhiwe nge-acetic acid kanye ne-phenol, ebonakala ngephunga layo elimnandi nelimnandi lezithelo elikhumbuza ezinye izinongo zokwenziwa. Lolu ketshezi olungenambala luvame ukusetshenziswa ekukhiqizeni amakha, izinongo, kanye nesinyibilikisi ekwelashweni okuhlukahlukene kwamakhemikhali. Ngaphezu kokusetshenziswa kwayo ezimbonini zokudla nezimonyo, i-phenyl acetate isebenza njengesisekelo sokwakha ekuhlanganiseni izinto eziphilayo futhi inezicelo ekukhiqizeni imithi. Ubuthi bayo obuphansi buthuthukisa ukusetshenziswa kwayo emikhakheni eminingi yezimboni ngenkathi kudingeke izinyathelo zokuqapha ezifanele zokuphatha.
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I-7-Hydroxycoumarin CAS:93-35-6
I-7-Hydroxycoumarin iyinhlanganisela yemvelo etholakala emndenini we-coumarin, ebonakala ngesakhiwo sayo esinuka kamnandi neqembu le-hydroxyl endaweni yesikhombisa. Yaziwa ngemisebenzi yayo ehlukahlukene yezinto eziphilayo, okuhlanganisa i-anticoagulant, i-antioxidant, kanye nezakhiwo zokulwa namagciwane. Le nhlanganisela iye yahlolwa ngezicelo zayo zokwelapha ezingaba khona ezimweni ezahlukene zezokwelapha, ikakhulukazi ezifweni zenhliziyo ngenxa yamandla ayo okuvimbela ukwakheka kwamahlule egazi. Ngaphezu kwalokho, isebenza njengethuluzi eliwusizo ocwaningweni lwe-biochemical, evame ukusetshenziswa njenge-fluorescent probe noma ekuhlolweni komsebenzi we-enzyme. Iphrofayili yayo yokuphepha kanye nokusebenza kwayo kuyaqhubeka kuhlolwa ezifundweni zesayensi.
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I-3-(4-Hydroxyphenyl)propionic acid CAS:501-97-3
I-3-(4-Hydroxyphenyl)propionic acid iyinhlanganisela yezinto eziphilayo enefomula yama-molecule C10H12O3. Iqukethe umgogodla we-propionic acid othathelwe indawo yiqembu le-para-hydroxyphenyl ku-carbon yesithathu. Lesi sakhiwo sinikeza izakhiwo ze-hydrophilic kanye ne-lipophilic, okwenza kube yinto efanele emikhakheni ehlukahlukene, kufaka phakathi imithi kanye ne-biochemistry. Le nhlanganisela idonsele isithakazelo ngenxa yemiphumela yayo engaba khona ye-antioxidant kanye ne-anti-inflammatory, engaba nomthelela empilweni nasekuphathweni kwezifo. Indima yayo njengesisekelo sokwakha ekwakhiweni kwamanye ama-molecule asebenzayo ithuthukisa ukubaluleka kwayo kumakhemikhali wezokwelapha kanye nesayensi yezinto ezibonakalayo.
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I-2-Phenylbutyric acid CAS:90-27-7
I-2-Phenylbutyric acid iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C12H14O2. Iqukethe umgogodla we-butyric acid othathelwe indawo yiqembu le-phenyl endaweni yesibili yekhabhoni. Le nhlanganisela enuka kamnandi inesithakazelo ekuhlanganisweni kwezinto eziphilayo kanye namakhemikhali ezokwelapha ngenxa yezindlela zayo zokwelapha ezingaba khona. Ukuba khona kweqembu le-phenyl kunezela ubunzima ezimpahleni zalo zamakhemikhali, okuthonya ukuncibilika kanye nomsebenzi webhayoloji. Ucwaningo nge-2-phenylbutyric acid luhlole indima yalo ezindleleni ezahlukahlukene ze-biochemical, futhi lungaba nemiphumela ekuthuthukiseni imithi, ikakhulukazi ku-neurobiology kanye nezinkinga ze-metabolic.
