I-Orlistat CAS: 96829-58-2 Umphakeli womkhiqizi

I-Orlistat iyi-semi-synthetic derivative ye-lipstatin, i-metabolite ehlukanisiwe ne-Streptomyces toxytricini.I-Tetrahydrolipstatin isebenza njenge-inhibitor enamandla, engenakuhlehliswa ye-pancreatic lipase.Ku-vivo, ivimbela ukumuncwa kwe-triglycerides kuyilapho ivumela ukumuncwa kwe-fatty acid.I-Tetrahydrolipstatin isetshenziswa kabanzi ekwelapheni ukukhuluphala.I-Orlistat inomphumela wesikhathi eside wokulawula isisindo esinciphisa futhi sigcine isisindo futhi sivimbele ukuphindaphinda.Ukusebenzisa i-Orlistat kunganciphisa ukwenzeka kwezinto eziyingozi ezihlobene nesisindo kanye nezifo, okuhlanganisa i-hypercholesterolemia, isifo sikashukela sohlobo lwe-2, ukubekezelela i-glucose ukukhubazeka, i-hyperinsulinemia, nomfutho wegazi ophakeme, futhi kunganciphisa okuqukethwe kwamafutha ezithweni.