I-N-Acetyl-D-Valine CAS:17916-88-0

N-I-Acetyl-D-Valine idlala indima ebalulekile kumakhemikhali e-peptide njengengxenye ebalulekile yokwenziwa kwama-peptide nama-peptidomimetics. Njenge-acetylated D-valine derivative, isebenza njengendlela eguquguqukayo yokungenisa izinsalela ezithile ze-chiral kumaketanga e-peptide ngokusebenzisa izindlela zokwenziwa kwama-peptide esigaba esiqinile kanye nesigaba sesisombululo. Abacwaningi kanye nosokhemisi basebenzisa i-N-Acetyl-D-Valine ukwenza ngezifiso ukulandelana kwama-peptide ngokulawula okunembile kwe-stereochemical, okuvumela ukwakheka kwamakhemikhali amasha asekelwe kuma-peptide ukuze kusetshenziswe izinto eziphilayo kanye nokwelapha. Ngaphezu kwalokho, i-N-Acetyl-D-Valine isetshenziswa njengesakhiwo se-chiral ekukhiqizweni kwezidakamizwa ezivamile, lapho i-stereochemistry yayo eyingqayizivele ibalulekile ekukhiqizweni kwezidakamizwa ze-chiral kanye namakhemikhali asebenzayo. I-chirality yayo kanye nokuqina kwayo kuyenza ibe yinto ebalulekile ekukhiqizweni kwemikhiqizo yezokwelapha enezakhiwo ze-pharmacological ezithuthukisiwe kanye nomsebenzi we-biological. Ngaphezu kwalokho, i-N-Acetyl-D-Valine ithola ukusetshenziswa ocwaningweni lwe-biochemical ukutadisha i-metabolism yama-amino acid, ukwakheka kwamaprotheni, kanye ne-enzyme kinetics. Indima yayo ekuphenyeni izindlela zamaseli kanye nezinqubo ze-metabolic inegalelo ekucaciseni imisebenzi yama-amino acid ezinhlelweni zezinto eziphilayo kanye nemiphumela yawo engaba khona empilweni nasezifweni. Ngamafuphi, i-N-Acetyl-D-Valine ibalulekile ekuthuthukiseni ucwaningo lwesayensi, intuthuko yemithi, kanye nezifundo ze-biochemical, inikeza ososayensi nochwepheshe ithuluzi eliguquguqukayo lokuhlola ukusetshenziswa okuhlukahlukene kwe-amino acid derivatives ekutholakaleni kwemithi, ukwenziwa kwe-peptide, kanye nophenyo lwe-biochemical.