I-N-(4-Aminobenzoyl)-beta-alanine CAS:7377-8-4

I-N-(4-Aminobenzoyl)-beta-alanine, noma i-Procaine, isetshenziswa kakhulu njenge-anesthetic yendawo ezinqubweni zezokwelapha nezamazinyo. Amandla ayo okuvimba okwesikhashana ukuqhutshwa kwemizwa avumela ukukhululeka kobuhlungu ngesikhathi sokuhlinzwa okuncane, ukwelashwa kwamazinyo, kanye nokungenelela kwesikhumba. Ngenxa yalokho, iyasiza ekunciphiseni ukungakhululeki kanye nokuthuthukisa induduzo yesiguli phakathi nalezi zinqubo. Ngaphezu kwezakhiwo zayo zokubulala izinzwa, i-N-(4-Aminobenzoyl)-beta-alanine ifundwe ngemiphumela yayo yokwelapha engaba khona ekuphatheni izimo ezithile zempilo. Ucwaningo luphakamisa ukusetshenziswa kwayo kanye neminye imithi yokubhekana nobuhlungu obuthile be-neuropathic, okuhlinzeka impumuzo kubantu abahlushwa yizinhlungu ezingapheli. Ngaphezu kwalokho, le nhlanganisela ithole ukusetshenziswa ocwaningweni lokuhlola njengethuluzi lokufunda umsebenzi we-neuronal kanye nezimpendulo zemithi. Ukusetshenziswa kwayo ezindaweni zelebhu kwenza ososayensi baqonde izinqubo zokubonisa izimpawu zemizwa futhi baphenye ukusebenzisana okungenzeka kwemithi kanye nezindlela zokusebenza. Ngaphezu kwalokho, i-N-(4-Aminobenzoyl)-beta-alanine ihlolwe ngendima yayo ekwakhiweni okwenzelwe imikhiqizo yokukhulula ubuhlungu endaweni. Ukufakwa kwayo kulezi zindlela kuhlose ukuhlinzeka ngemithi yokwelapha ubuhlungu bemisipha, izinhlungu zamalunga, kanye nokulimala okuncane, okufaka isandla ezixazululweni ezithengiswa ngaphandle kwemithi yokwelapha ubuhlungu ngaphandle kwemiphumela yesistimu. Sekukonke, i-N-(4-Aminobenzoyl)-beta-alanine, noma i-Procaine, idlala indima ebalulekile emikhakheni yezokwelapha neyemithi njenge-anesthetic yendawo, inikeza ukukhululeka ebuhlungwini ngesikhathi sezinqubo ezahlukene zezokwelapha kanye nokwelashwa kwamazinyo. Ukusetshenziswa kwayo okungenzeka kokwelapha ekuphatheni izinhlobo ezithile zobuhlungu kanye nokusebenza kwayo ocwaningweni kugcizelela kakhulu ukuguquguquka kwayo kanye nokubaluleka kwayo emiphakathini yezempilo kanye nesayensi.