I-Mecillinam CAS:32887-01-7

I-Mecillinam, eyaziwa nangokuthi i-pivmecillinam, iyi-antibiotic ye-penicillin ene-spectrum encane enomsebenzi oyinhloko wokulwa namagciwane angenayo i-Gram. Ingesigaba sama-antibiotic e-amidinopenicillin futhi ihlobene ngokwesakhiwo ne-ampicillin. I-Mecillinam ibonakala ngokuqondene kwayo nokuhlasela i-Enterobacteriaceae, okuhlanganisa izinhlobo ze-Escherichia coli ne-Klebsiella. Inemiphumela yayo yokubulala amagciwane ngokuvimbela ukwakheka kodonga lwamaseli ebhaktheriya ngokubopha amaprotheni ahlanganisa i-penicillin. I-Mecillinam itholakala ekwakhiweni komlomo, okwenza ifanelekele ukwelashwa kwezifo zomgudu womchamo kanye nezinye izifo ezitholakala endaweni ethile ezibangelwa izinto eziphilayo ezingenayo i-Gram.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela:

I-Mecillinam ivame ukusetshenziswa emitholampilo yokwelapha izifo zomgudu womchamo ezingeyona inkimbinkimbi (ama-UTI) ezibangelwa amagciwane angenamandla e-Gram, ikakhulukazi i-Escherichia coli. Umsebenzi wayo omncane uvumela ukwelashwa okuqondisiwe ngokumelene nezifo ezivamile ze-uropathogenic ngenkathi kunciphisa ukuphazamiseka kwezitshalo ezivamile. I-Mecillinam ivame ukuthandwa ngama-UTI ngenxa yokusebenza kwayo kahle, iphrofayili yokuphepha, kanye namathuba aphansi okukhuthaza ukumelana. Ngaphezu kwama-UTI, i-mecillinam isetshenziselwa ukuphathwa kwezinye izifo zasendaweni, njenge-prostatitis kanye nezifo zangaphansi zokuphefumula, lapho kuhileleka khona amagciwane angenamandla e-Gram. Umsebenzi wayo wokukhetha ngokumelene ne-Enterobacteriaceae wenza kube yindlela ebalulekile ekwelapheni lezi zifo ezithile ngenkathi igwema ukusetshenziswa okungadingekile kwama-antibiotic e-broad spectrum. Ukwakheka kwe-Mecillinam ngomlomo kanye nezakhiwo ezinhle ze-pharmacokinetic kwenza kube lula ekwelapheni izifo ezincane kuya kweziphakathi ngaphandle kwesibhedlela, okuvumela iziguli ukuthi ziqede inkambo yazo yokwelapha ngempumelelo. Ukusebenza kwayo okuzinzile ekuqondiseni amagciwane angenamandla e-Gram kugcizelela ukubaluleka kwayo ekuphathweni kwezifo zasendaweni. Ngaphezu kwalokho, i-mecillinam isetshenziswa kwezinye izindlela zokuvimbela ukuvimbela ama-UTI aphindaphindayo noma njengendlela yokuvimbela ukutheleleka ngaphambi kokuhlinzwa ezinqubweni zokuhlinzwa lapho amagciwane angenayo i-Gram ebeka khona ingozi yokutheleleka. Amandla ayo okufinyelela amazinga aphezulu ezicutshini zomchamo nokulwa ngempumelelo nama-uropathogens kuyenza ibe yinto ewusizo yokuvimbela ezimweni ezithile zemitholampilo. Sekukonke, i-mecillinam isebenza njengenketho ewusizo yama-antibiotic ekwelapheni izifo zasendaweni ezibangelwa amagciwane angenayo i-Gram asengozini, inikeza odokotela indlela yokwelapha eqondiwe futhi ephumelelayo enengozi ephansi yokuthuthukiswa kokumelana. Indima yayo njenge-agent encane yenza ibe ithuluzi elibalulekile emizamweni yokuphatha ama-antimicrobial, ikhuthaza ukusetshenziswa okufanele kwama-antibiotic kanye nokunciphisa ukuvela kwezinto eziphilayo ezimelana nemithi eminingi.

Isampula Yomkhiqizo:

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C15H23N3O3S
Ukuhlolwa	99%
Ukubukeka	impuphu emhlophe
Inombolo ye-CAS	32887-01-7
Ukupakisha	Encane futhi enkulu
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.