I-Losartan Potassium CAS: 124750-99-8 Umhlinzeki Womkhiqizi

I-Losartan potassium iyi-antiagonist yokuqala enamandla futhi ekhethiwe ye-non-peptide angiotensin II (AT II) AT1 receptor engeniswe emakethe njenge-antihypertensive yomlomo kanye ngosuku. Iyasebenza futhi ihlala isikhathi eside ekulawuleni umfutho wegazi kumagundane ane-hypertension ezenzakalelayo, ezigulini ezine-essential hypertension kanye nalezo ziguli ezine-renal effect. Ngaphandle kwalokho, ucwaningo lwamuva luphakamise ukuthi i-losartan inenzuzo yokuguqula ukungasebenzi kahle okuhlobene nobudala ekugcineni umfutho wegazi ojwayelekile kanye nokusetshenziswa kwamandla eseli ku-mitochondria futhi cishe ingasetshenziswa ukwelapha i-left ventricular hypertrophy. Ingasetshenziswa futhi njenge-ejenti ehlukile yokwelapha ukungasebenzi kahle kwe-systolic, i-myocardial infarction, isifo se-coronary artery, kanye nokwehluleka kwenhliziyo.