I-Losartan Potassium CAS:124750-99-8 Umkhiqizi Womhlinzeki

I-Losartan potassium iyisitha sokuqala esinamandla nesikhethiwe se-non-peptide angiotensin II (AT II) AT1 receptor antagonist yethulwa emakethe njenge-antihypertensive yomlomo kanye ngosuku.Isebenza kahle futhi ihlala isikhathi eside ekulawuleni umfutho wegazi kumagundane ane-hypertension ezenzakalelayo, ezigulini ezinomfutho wegazi ophakeme obalulekile ngaphezu kwalezo ziguli ezinokukhubazeka kwezinso.Ngaphandle kwalokho, ucwaningo lwakamuva luphakamise ukuthi i-losartan inenzuzo ukubuyisela emuva ukungasebenzi kahle okuhlobene nobudala ekugcineni umfutho wegazi ojwayelekile kanye nokusetshenziswa kwamandla amaselula ku-mitochondria futhi ingasetshenziswa ukwelapha i-hypertrophy ye-ventricular kwesokunxele.Ingase futhi isetshenziswe njengenye indlela yokwelapha ukungasebenzi kahle kwe-systolic, i-myocardial infarction, isifo se-coronary artery, kanye nokuhluleka kwenhliziyo.