I-L-5-Methyltetrahydrofolatecalcium CAS:151533-22-1

I-L-5-Methyltetrahydrofolate calcium idlala indima ebalulekile ekubhekaneni nokuntuleka kwe-folate nokusekela imisebenzi ebalulekile yezinto eziphilayo. Njengendlela esebenzayo ye-folate, ivame ukusetshenziswa ezithasiselweni zokudla okunempilo kanye nemithi ukuze inikeze umthombo we-folate otholakala kalula, obalulekile ekwakhiweni kwe-DNA, ukuhlukaniswa kwamaseli, kanye nokugcinwa kwempilo yonke yamaseli. Emkhakheni wokunakekelwa kwangaphambi kokubeletha kanye nempilo kamama, i-L-5-Methyltetrahydrofolate calcium isetshenziselwa ukuvimbela ukukhubazeka kwe-neural tube nokusekela ukukhula kwengane ngesikhathi sokukhulelwa. Amazinga anele e-folate abalulekile ekuvimbeleni ukukhubazeka kokuzalwa nokuqinisekisa ukuthuthukiswa okufanele kwezinzwa, okwenza i-L-5-Methyltetrahydrofolate calcium ibe yingxenye ebalulekile yezithako zokubeletha nokudla okuqinisiwe okuhloselwe ukusekela impilo kamama nosana. Ngaphezu kwalokho, i-L-5-Methyltetrahydrofolate calcium ihilelekile ekuphathweni kwezimo ezithile zezokwelapha, okuhlanganisa i-megaloblastic anemia kanye nesifo senhliziyo. Indima yayo ekwenzeni lula ukwakheka kwe-DNA nokulawula amazinga e-homocysteine ​​​​inegalelo ekubalulekeni kwayo kokwelapha ekubhekaneni nalezi zinkinga zempilo, lapho ukwengezwa kwe-folate kunconywa njengengxenye yamasu okuphatha izifo nokuvimbela. Ngaphezu kwalokho, i-L-5-Methyltetrahydrofolate calcium isetshenziswa njengesithasiselo ekwelapheni ukucindezeleka nezinye izifo zengqondo. I-Folate idlala indima ekuhlanganisweni nasekulawulweni kwama-neurotransmitter, futhi ukungezelelwa kwayo, ikakhulukazi ngefomu elisebenzayo le-L-5-Methyltetrahydrofolate, kuye kwafundwa amandla ayo okusekela ukulawulwa kwemizwa kanye nenhlalakahle yengqondo, kungaba njengokungenelela okuzimele noma kuhlanganiswe nemithi yendabuko yokucindezeleka. Ngaphezu kwalokho, i-L-5-Methyltetrahydrofolate calcium isetshenziswa emithini yokwelapha kanye nokungenelela kokudla okunempilo, lapho ukuhlukahluka komuntu ngamunye kumetabolism ye-folate kanye nezici zofuzo kungadinga izindlela ezilungiselelwe zokwengeza i-folate. Ukusetshenziswa kwayo ekudleni okunembile kanye nokunakekelwa kwempilo komuntu siqu kugcizelela ukubaluleka kwayo ekwenzeni ngcono imiphumela yezempilo ngokusekelwe ezidingweni zomuntu ngamunye kanye nokuthambekela kwezakhi zofuzo. Sekukonke, i-L-5-Methyltetrahydrofolate calcium idlala indima ebalulekile ekungezelweni kokudla okunempilo, ukunakekelwa kwangaphambi kokubeletha, ukuphathwa kwezifo, kanye nokusekelwa kwempilo yengqondo, inikeza izinhlelo zokusebenza ezahlukahlukene ekukhuthazeni impilo iyonke kanye nokubhekana nezimo ezithile zezokwelapha kubantu abahlukahlukene.