I-Heparin sodium CAS:9041-08-1

Umphumela ekuqhekekeni kwegazi: I-heparin sodium isebenza ngokuvimbela ukwakheka kwamahlule egazi. Ibopha ku-antithrombin, iphrotheni yemvelo emzimbeni, futhi ithuthukisa ikhono layo lokuvimbela izinto ezivala igazi, ikakhulukazi i-thrombin kanye ne-factor Xa. Lokhu kuvimbela ukuguqulwa kwe-fibrinogen ibe yi-fibrin, ukwakheka kwe-thrombin, kanye nokwakheka kwamahlule egazi okulandelayo.

Ukuvimbela i-deep vein thrombosis (DVT) kanye ne-pulmonary embolism (PE): I-heparin sodium ivame ukusetshenziswa ukuvimbela ukwakheka kwamahlule egazi emithanjeni (DVT) bese kamuva iye emaphashini (PE). Ivame ukunikezwa njengokwelashwa kokuvimbela ngaphambi kokuhlinzwa, ngesikhathi sokulaliswa esibhedlela, noma ezigulini ezisengozini enkulu yokwakheka kwamahlule.

Ukwelashwa kwamahlule egazi akhona: I-Heparin sodium ingasetshenziswa futhi ngokwezokwelapha ukwelapha amahlule egazi akhona. Kulezi zimo, iyasiza ekuvimbeleni ukukhula kwamahlule futhi yehlise ingozi yezinkinga, njengohlangothi noma ukuhlaselwa yinhliziyo.

I-Hemodialysis kanye nokujikeleza kwegazi ngaphandle komzimba: I-Heparin sodium isetshenziswa ngesikhathi sezinqubo ze-hemodialysis kanye nokujikeleza kwegazi ngaphandle komzimba ukuvimbela ukujiya kwegazi ngaphandle komzimba. Ingezwa ku-dialysate noma ijikelezwe ngomshini we-cardiopulmonary bypass ukuvimbela ukujiya kwegazi ngaphakathi kwala madivayisi.

Ukuqapha ukwelashwa kwe-anticoagulant: I-Heparin sodium isetshenziselwa futhi ukuqapha ukusebenza kahle kweminye imithi ye-anticoagulant, njenge-warfarin. Isikhathi se-partial thromboplastin (PTT) noma isikhathi se-activated partial thromboplastin (aPTT) singalinganiswa ukuqinisekisa amazinga okwelapha e-anticoagulant nokulungisa umthamo ngokufanele.

Ukuvimbela ukukhulelwa kanye nezimo ezithile zezokwelapha: I-heparin sodium ingase inikezwe abesifazane abakhulelwe abasengozini enkulu yokuphazamiseka kwegazi, njenge-deep vein thrombosis noma ukuphuphuma kwesisu okuphindaphindiwe. Iphinde isetshenziswe kubantu abanezimo ezithile zezokwelapha, njenge-antiphospholipid syndrome noma ezinye izimo zenhliziyo, ukuvimbela ukwakheka kwamahlule egazi.