I-Hemin = I-Chlorohemin CAS:16009-13-5 Intengo Yomkhiqizi

Ukuthuthwa komoya-mpilo: I-Hemin iyisici esibalulekile se-hemoglobin, evumela amangqamuzana abomvu egazi ukuthi abophe futhi athwale umoya-mpilo aye ezicutshini kuwo wonke umzimba. Lokhu kwenza kube lula ukungenisa umoya-mpilo futhi kusekele ukuphefumula kwamaseli.

Ukwenziwa kwe-Heme: I-Hemin ihilelekile ekwakhiweni kwe-heme, i-molecule ebalulekile ekusebenzeni kwama-hemoprotein ahlukahlukene. Lokhu kufaka phakathi i-myoglobin, ama-cytochrome, nama-catalases, adlala indima ebalulekile ekugcinweni komoya-mpilo, ukuthuthwa kwama-electron, kanye nokusetshenziswa kwamaseli.

Umsebenzi we-Coenzyme: I-Hemin isebenza njenge-coenzyme yama-enzyme amaningana ahilelekile ku-heme kanye ne-bilirubin metabolism. Isebenza njengesikhuthazi futhi yenza kube lula lokhu kusabela kwama-enzyme, iqinisekisa ukucutshungulwa kanye nokususwa kwe-heme kanye ne-bilirubin emzimbeni.

Ukulawulwa kokubonakaliswa kwezakhi zofuzo: I-Hemin inekhono lokulawula ukubonakaliswa kwezakhi zofuzo ngokusebenzisana nochungechunge oluthile lwe-DNA, olwaziwa ngokuthi ama-promoters, kanye nokuthonya ukuqoshwa kwezakhi zofuzo eziqondiwe. Lesi sici sisetshenziswe ocwaningweni lwelabhorethri ukutadisha imiphumela ye-hemin ezindleleni ezithile zamaseli kanye nezinqubo zesifo.

Ukwelashwa nge-Porphyria: Ukwelashwa nge-Hemin kusetshenziswa ekwelapheni i-porphyria, iqembu lezinkinga zofuzo ezibonakala ngamaphutha ekwakhekeni kwe-heme. Ngokuhlinzeka nge-hemin yangaphandle, kusiza ukubuyisela amazinga e-heme afanele, kunciphisa izimpawu futhi kuvimbele ukuhlaselwa okubukhali okubangelwa ukuqongelela kwezinto ezinobuthi ze-heme.