I-H-Glu(OBzl)-OBzl·I-Tos CAS:2791-84-6

I-H-Glu(OBzl)-OBzl·Tos isetshenziswa kabanzi ekwakhiweni kwe-peptide, isebenza njengesisekelo esibalulekile sokwakha ama-peptide anezici ezithile zesakhiwo nokusebenza. Ukuba khona kwamaqembu e-benzyl ester kuthuthukisa ukusebenzisana kwe-hydrophobic kwe-peptide, okwenza kube wusizo ekudaleni ama-peptide anezakhiwo ezilungiselelwe njengokuthuthukiswa kokungena kwe-membrane noma ukucaciswa kwethagethi. Ngaphezu kwalokho, i-compound isetshenziswa ekuthuthukisweni kwemithi ukudala izidakamizwa ezisekelwe ku-peptide ezinokuzinza okuthuthukisiwe kanye nokutholakala kwezinto eziphilayo, okungenzeka kuholele emiphumeleni yokwelapha ethuthukisiwe. Ngaphezu kwalokho, ocwaningweni lwe-proteomics kanye nolwe-biochemical, i-H-Glu(OBzl)-OBzl·Tos ingasetshenziswa ukutadisha ukusebenzisana kwamaprotheni namaphrotheni, ukuphenya umsebenzi we-enzymatic, nokuhlola amandla okugoqa amaprotheni. Isakhiwo sayo esilungiselelwe sivumela abacwaningi ukuthi bahlole ubunzima bezinqubo zamaseli kanye nezindlela zezifo, okufaka isandla ekuthuthukisweni kokuqonda impilo kanye ne-pathology. Ukuguquguquka kanye nokuhambisana kwe-compound nezimo ezahlukahlukene zokuhlola kwenza kube yingxenye ebalulekile yokucacisa ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Ngamafuphi, i-H-Glu(OBzl)-OBzl·Tos imelela ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide anezakhiwo ezithile futhi ahlukanise izindlela eziyisisekelo zezinqubo zezinto eziphilayo, ngaleyo ndlela enikela ekuthuthukisweni kwezokwelapha kanye ne-biotechnology.