H-Arg-OBut·2HCl CAS:87553-73-9

I-H-Arg-OBut·2HCl idlala indima ebalulekile ekuhlanganisweni nasekuguqulweni kwe-peptide ngenxa yekhono layo lokuvikela iqembu le-guanidine le-L-arginine. Lokhu kuvikelwa kuvumela ukusabela okukhethiwe namanye amaqembu asebenzayo, kusiza ukwakhiwa okunembile kokulandelana kwe-peptide futhi kuvumela ukutadisha ubudlelwano besakhiwo nomsebenzi kuma-peptide asebenzayo ngokwezinto eziphilayo. Ekutholakaleni nasekuthuthukisweni kwezidakamizwa, i-H-Arg-OBut·2HCl inegalelo ekudalweni kwemithi esekwe kuma-peptide kanye nama-bioconjugates. Indima yayo ekuvikelweni kwama-peptide kanye nezinqubo zokususa ukuvikela ezilandelayo ibalulekile ekwakhiweni nasekukhiqizweni kwama-ejenti amasha okwelapha anezicelo ezingaba khona ekulethweni kwemithi okuqondiwe kanye nemithi enembile. Ngaphezu kwalokho, ocwaningweni lwe-biochemical, i-H-Arg-OBut·2HCl ivumela ososayensi ukuthi bahlole futhi balawule imisebenzi kanye nokusebenzisana kwama-peptide namaprotheni. Ngokuhlinzeka ngendlela yokuvikela ngokukhetha iqembu le-guanidine le-L-arginine, abacwaningi bangacacisa izinqubo zezinto eziphilayo futhi baphenye izinhloso ezingaba khona zokuthuthukiswa kwemithi, ngaleyo ndlela bandise ukuqonda kwezindlela zama-molecule ezintweni eziphilayo. Uma usebenza ne-H-Arg-OBut·2HCl, ukunamathela ezimisweni zokuphepha zelebhu ezimisiwe kanye neziqondiso zokuphatha kubalulekile ukuqinisekisa ukusetshenziswa okufanele nokunciphisa izingozi ezihlobene nama-reagent amakhemikhali. Ukuqonda ukusabela okuthile kanye nokusetshenziswa kwe-H-Arg-OBut·2HCl ngaphakathi komongo wokwenziwa nokuguqulwa kwe-peptide kubalulekile ekwenzeni izivivinyo eziphumelelayo nokufeza imiphumela yesayensi efiselekayo.