I-Fmoc-Arg(NO2)-OH CAS:58111-94-7

I-Fmoc-Arg(NO2)-OH idlala indima ebalulekile ekwakhiweni kwe-peptide, ikakhulukazi ezimweni ezidinga ukufakwa kokusebenza kwe-nitro kumaketanga e-peptide. Iqembu elivikela i-Fmoc livikela iqembu lama-amino le-arginine, liqinisekisa ukusabela okukhethayo ngesikhathi sokusabela kokuhlanganisa okulandelayo. Ukuba khona kweqembu le-nitro kunikeza izakhiwo zamakhemikhali ezihlukile, okwenza i-Fmoc-Arg(NO2)-OH ibe ithuluzi elibalulekile ekwakhiweni nasekuthuthukisweni kwama-peptide anemisebenzi efanelekile. Abacwaningi basebenzisa i-Fmoc-Arg(NO2)-OH ekudalweni kwama-peptide anokuguqulwa kwe-nitro, isici esibalulekile ezifundweni ezihlobene nama-peptide alwa namagciwane, i-bioconjugation, kanye ne-chemistry yezokwelapha. Ukwengezwa okulawulwayo kweqembu le-nitro kuvumela ukuguqulwa okunembile kwezakhiwo ze-peptide, okuthonya umsebenzi wezinto eziphilayo kanye nokusebenzisana nama-molecule aqondiwe. Ngaphezu kwalokho, ukuhambisana kwe-Fmoc-Arg(NO2)-OH nezindlela ezijwayelekile zokwenziwa kwe-peptide kuthuthukisa ukusebenza kwayo ekwakhiweni kwe-peptide yesigaba esiqinile (i-SPPS). Le nhlanganisela ithola ukusetshenziswa ekwakhiweni kwama-peptide okuhlolwa kwezinto eziphilayo, ukuthuthukiswa kwemithi, kanye nesayensi yezinto. Ngamafuphi, i-Fmoc-Arg(NO2)-OH ivela njengengxenye eguquguqukayo neyisu kumakhemikhali e-peptide, inika amandla abacwaningi ukuthi bahlole futhi basebenzise izakhiwo ze-peptide ukuze kufezwe imigomo eyahlukene yesayensi neyokwelapha.