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I-Pristinamycin CAS:270076-60-3
I-Pristinamycin umuthi ohlanganisiwe wama-antibiotic oqukethe izingxenye ezimbili ezisebenzayo, i-pristinamycin I kanye ne-pristinamycin II. Iyingxenye yeqembu lama-antibiotic e-streptogramin futhi ibonisa imisebenzi yamagciwane kanye neyokubulala amagciwane ngokumelene namagciwane ahlukahlukene ane-gram-positive, okuhlanganisa i-Staphylococcus aureus kanye ne-Streptococcus pneumoniae. I-Pristinamycin isebenza ngokuvimbela ukwakheka kwamaprotheni amabhaktheriya, okwenza iphumelele ekwelapheni izifo zesikhumba nezicubu ezithambile, izifo zokuphefumula, kanye nezinye izifo zamabhaktheriya ezibangelwa izinto eziphilayo ezisengozini.
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I-Ribostamycin sulfate CAS:53797-35-6
I-Ribostamycin sulfate iyi-aminoglycoside antibiotic etholakala ku-Streptomyces griseoluteus. Ibonisa umsebenzi onamandla wokubulala amagciwane ngokumelene nezinhlobo eziningi zamagciwane angenayo i-gram kanye namanye angenayo i-gram ngokuvimbela ukwakheka kwamaprotheni. I-Ribostamycin sulfate ivame ukusetshenziswa ekwelapheni izifo ezahlukahlukene, okuhlanganisa izifo zomgudu womchamo, izifo zomgudu wokuphefumula, izifo zesikhumba nezicubu ezithambile, kanye ne-septicemia ebangelwa izinhlobo zamagciwane ezisengozini.
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I-Rifampicin CAS:13292-46-1
I-Rifampicin, eyaziwa nangokuthi i-rifampin, umuthi wama-antibiotic obanzi ongoweqembu le-rifamycin. Isetshenziswa kabanzi ekwelapheni isifo sofuba, uchoko, kanye nezinye izifo zamagciwane. I-Rifampicin isebenza ngokuvimbela ukwakheka kwe-RNA kumagciwane, ngaleyo ndlela iphazamise ikhono lawo lokuzalana nokusinda. Ngenxa yomsebenzi wayo onamandla wokulwa namagciwane kanye nokusebenza kahle ngokumelene nezinhlobo ze-mycobacterial, i-rifampicin iyisici esibalulekile semithi yokwelapha ehlanganisiwe yesifo sofuba kanye nezinye izifo ezithathelwanayo.
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I-Puromycin dihydrochloride CAS:58-58-2
I-Puromycin dihydrochloride iyisivimbeli esinamandla sokwenziwa kwama-antibiotic kanye namaprotheni esivela ku-Streptomyces alboniger. Ivame ukusetshenziswa ocwaningweni lwe-molecular biology ukuvimbela ngokukhetha ukwakheka kwamaprotheni emaseli ngokuqeda ukuhumusha ngaphambi kwesikhathi ngesikhathi sokwenziwa kwamaprotheni. I-Puromycin dihydrochloride ifakwa kumaketanga e-peptide asafufusa, okuholela ekukhululweni kwama-polypeptide angaphelele kanye nokufa kwamaseli ekugcineni. Ngenxa yendlela yayo yokusebenza eyingqayizivele, i-puromycin dihydrochloride iyithuluzi eliwusizo lokufunda ukwakheka kwamaprotheni, umsebenzi we-ribosome, ukubonakaliswa kwezakhi zofuzo, kanye nokuphila kwamaseli ezindaweni zokuhlola.
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I-Protionamide CAS:14222-60-7
I-Protionamide umuthi wama-antibiotic ongoweqembu le-thioamide, osetshenziswa kakhulu ekwelapheni isifo sofuba esingamelana nemithi eminingi. Isebenza ngokuvimbela ukwakheka kwe-mycolic acid odongeni lweseli lamagciwane, okuholela ekubhujisweni kwesifo sofuba se-Mycobacterium. I-Protionamide ivame ukunikezwa ihlanganiswe neminye imithi yokulwa nesifo sofuba njengengxenye yohlelo lokwelapha oluphelele lwezinhlobo zesifo sofuba ezingamelana nemithi.
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I-Potassium clavulanate CAS: 61177-45-5
I-Potassium clavulanate iyisivimbeli se-β-lactamase esivame ukuhlanganiswa nama-antibiotic athile ukuze kuthuthukiswe ukusebenza kwawo ngokumelene nokutheleleka ngamagciwane. Isebenza ngokuvimbela ukuwohloka kwe-antibiotic ngama-enzyme amagciwane, ngaleyo ndlela yandisa ububanzi bomsebenzi futhi ithuthukise imiphumela yokwelashwa. I-Potassium clavulanate ivame ukusetshenziswa emikhiqizweni ehlanganisiwe nama-antibiotic afana ne-amoxicillin ukwelapha izifo ezahlukahlukene zamagciwane.
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I-Retapamulin CAS:224452-66-8
I-Retapamulin umuthi osetshenziswa njenge-antibiotic otholakala endaweni yemithi we-pleuromutilin. Usetshenziselwa ukwelapha izifo zesikhumba ezibangelwa amagciwane, ikakhulukazi i-impetigo ebangelwa izinhlobo ezisengozini ze-Staphylococcus aureus kanye ne-Streptococcus pyogenes. I-Retapamulin isebenza ngokuvimbela ukwakheka kwamaprotheni amagciwane, okuholela ekuqedweni kwamagciwane athelelanayo kanye nokuxazulula ukutheleleka kwesikhumba.
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I-Staurosporine, i-streptomyces staurosporeus CAS:62996-74-1
I-Staurosporine iwumkhiqizo wemvelo ohlukaniswe nebhaktheriya i-Streptomyces staurosporeus. Ihlukaniswa njenge-alkaloid enamandla enomsebenzi obalulekile webhayoloji, ikakhulukazi ekuvimbeleni ama-protein kinase kanye nokukhuthaza i-apoptosis yamaseli. I-Staurosporine ifundwe kabanzi ngezakhiwo zayo zemithi, okuhlanganisa amandla ayo okulwa nomdlavuza kanye nendima yayo njengethuluzi locwaningo ezifundweni zokubonisana kwamaseli.
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Usawoti we-phosphomycin disodium CAS:26016-99-9
Usawoti we-Phosphomycin disodium uwumuthi olwa namagciwane obanzi osetshenziswa ekwelapheni izifo ezahlukahlukene zamagciwane. Ungowesigaba sama-phosphonic acid futhi usebenza ngokuvimbela ukwakheka kodonga lwamaseli ebhaktheriya. Le mpuphu emhlophe ekristalu incibilika kakhulu emanzini futhi ivame ukunikezwa ngemithambo noma ngomlomo. Usawoti we-Phosphomycin disodium waziwa ngokusebenza kwawo ngokumelene namagciwane ahlukahlukene ane-gram-positive kanye ne-gram-negative, okwenza kube ukukhetha okuhlukahlukene kokwelapha izifo.
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I-Phleomycin CAS:11006-33-0
I-Phleomycin iyi-antibiotic enamandla esetshenziswa ocwaningweni lwe-molecular biology ekukhetheni amaseli aqukethe i-gene ethakaselwayo. Njengoba inendlela yokusebenza ehilela ukuqhekeka kwe-DNA, i-Phleomycin iyasebenza ngokumelene namagciwane ahlukahlukene futhi isetshenziswe kabanzi ezinhlelweni zocwaningo ezahlukahlukene. Le antibiotic ivame ukusetshenziswa kanye nezinye izimpawu zokukhetha ukudala imigqa yamaseli ezinzile ngokuguqulwa kwezakhi zofuzo okufunwayo. I-Phleomycin itholakala kokubili ngezindlela zoketshezi kanye ne-powder, okwenza ibe lula futhi isebenziseke kalula ezilungiselelweni ezahlukene zokuhlola. Abacwaningi bayakwazisa ukusebenza kwayo okuphezulu kanye nokuthembeka ekukhetheni amaseli aguquliwe, okwenza kube ithuluzi eliwusizo ezifundweni zobunjiniyela bezakhi zofuzo.
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Usawoti we-potassium we-Penicillin V CAS:132-98-9
Usawoti we-potassium we-Penicillin V uwumuthi olwalwa nomlomo wokwelapha izifo ezibangelwa amagciwane. Uqukethe i-penicillin V, uhlobo lwe-potassium salt lwe-phenoxymethylpenicillin. I-Penicillin V isebenza ngokuphazamisa ukwakheka kwe-peptidoglycan odongeni lweseli lamagciwane. Lokhu kwenza buthaka udonga lweseli futhi kubulale noma kuvimbele ukukhula kwamagciwane asengozini. Itholakala njengamaphilisi noma ama-suspension athathwa ngomlomo ukuze kutholakale ukwelashwa kwezifo ezincane kuya kweziphakathi.
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Usawoti we-sodium we-Penicillin G (usawoti we-sodium we-Benzylpenicillin) I-CAS:69-57-8
Usawoti we-sodium we-Penicillin G uwumuthi olwakhiwe yi-penicillin G ngesimo sawo sosawoti we-sodium. Usebenza ngokuvimbela ukwakheka kwezingqimba ze-peptidoglycan ezindongeni zamaseli ebhaktheriya, ukubulala amabhaktheriya asengozini. Usawoti we-sodium we-Penicillin G utholakala njengamakristalu amhlophe noma acishe abe mhlophe noma impuphu okumele ihlanganiswe kabusha ibe yisisombululo ngaphambi kokujova. Uhlinzeka ngokulethwa kwe-penicillin G ngendlela ehlelekile yokwelapha izifo zamabhaktheriya.
