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i-tert-butyl 4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate CAS: 932398-74-8
I-Tert-butyl 4-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate, evame ukubizwa ngokuthi i-compound Y, iyinhlanganisela yamakhemikhali eguquguqukayo enezicelo ezibalulekile embonini yezokwelapha kanye nesayensi yezinto ezibonakalayo. Ngefomula yama-molecule ye-C15H21NO3, le nhlanganisela ifaka i-scaffold ye-quinoline ehlukile ethathelwe indawo yiqembu le-tert-butyl kanye nokusebenza kwe-carboxylate. Isakhiwo sayo esihlukile sinikeza izakhiwo ezifiselekayo ezibalulekile ekusetshenzisweni okuhlukahlukene, kusukela ekwakhiweni kwemithi kuya kumakhemikhali wezinto ezibonakalayo. Njengengxenye ebalulekile ekuhlanganisweni kwezinto eziphilayo, isebenza njengesisekelo sokuthuthukiswa kwemithi emisha kanye nezinto ezisebenzayo, iqhuba ukusungula izinto ezintsha emikhakheni ehlukahlukene.
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I-Semaglutide CAS:910463-68-2
I-Semaglutide iyi-peptide-1 (GLP-1) receptor agonist enamandla efana ne-glucagon esetshenziswa ekwelapheni isifo sikashukela sohlobo 2 kanye nokukhuluphala. Ifana ne-hormone ye-GLP-1 engokwemvelo, i-semaglutide inikeza umsebenzi wezokwelapha isikhathi eside ngenxa yokuguqulwa kwayo nge-fatty acid side chain. Ngefomula yayo yama-molecule C187H291N45O59, isigamu sempilo esandisiwe se-semaglutide sivumela ukumuncwa kanye ngesonto, kuthuthukisa ukulula kwesiguli kanye nokunamathela ezindleleni zokwelapha.
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I-Linaclotide CAS: 851199-59-2
I-Linaclotide iyi-agonist ye-guanylate cyclase-C (GC-C) esetshenziselwa ukwelapha ukuqunjelwa okungapheli kanye ne-irritable bowel syndrome ene-constipation (IBS-C). Ifana ne-peptide ye-guanylin endogenous, i-linaclotide ibopha ngokukhetha futhi isebenze ama-receptor e-GC-C endleleni yokugaya ukudla, okuholela ekwandeni kokukhiqizwa koketshezi lwamathumbu kanye nesikhathi sokuhamba esisheshayo. Ngefomula yayo yama-molecule C59H79N15O21S6, i-linaclotide inikeza indlela eqondiwe yokuqeda ukuqunjelwa nokunciphisa ukungakhululeki kwesisu okuhambisana ne-IBS-C, ithuthukise ikhwalithi yokuphila kweziguli.
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I-Liraglutide CAS:204656-20-2
I-Liraglutide iyi-peptide-1 (GLP-1) receptor agonist enamandla esetshenziswa ekwelapheni isifo sikashukela sohlobo 2 kanye nokukhuluphala. Ifana ne-hormone ye-GLP-1 engokwemvelo, i-liraglutide inikeza umsebenzi wezokwelapha isikhathi eside ngenxa yokuguqulwa kwayo nge-fatty acid side chain. Ngefomula yayo yama-molecule C172H265N43O51, isigamu sempilo esandisiwe se-liraglutide sivumela ukumuncwa kanye ngosuku, kuthuthukisa ukulula kwesiguli kanye nokunamathela ezindleleni zokwelapha.
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i-ethyl 4-(hydroxymethyl)-1H-pyrazole-5-carboxylate I-CAS:61453-49-4
I-Ethyl 4-(hydroxymethyl)-1H-pyrazole-5-carboxylate, ikhemikhali eguquguqukayo, ibalulekile emikhakheni yezokwelapha kanye ne-agrochemical. Ngefomula yama-molecule i-C8H10N2O3, ifaka indandatho ye-pyrazole ethathelwe indawo yiqembu le-ethyl, ingxenye ye-hydroxymethyl, kanye nokusebenza kwe-carboxylate. Le nhlanganisela isebenza njengesixhumi esibalulekile ekuhlanganisweni kwezinto eziphilayo, ikhuthaza ukuthuthukiswa kwemithi ehlukahlukene kanye namakhemikhali ezolimo. Isakhiwo sayo esiyingqayizivele kanye namaqembu asebenzayo kwenza kube yisisekelo sokwakha esiguquguqukayo sokwenza ama-molecule ngezinhlelo zokusebenza ezahlukahlukene, okuqhuba ukusungula izinto ezintsha ezimbonini eziningi.
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I-Ethyl 4-cyanopiperidine-4-carboxylatehydrochloride CAS:123730-64-3
I-Ethyl 4-cyanopiperidine-4-carboxylate hydrochloride, ikhemikhali ebalulekile, idumile embonini yezemithi kanye nezolimo. Ngefomula yama-molecule i-C9H14ClNO2, ifaka indandatho ye-piperidine ethathelwe indawo yiqembu le-ethyl kanye nengxenye ye-cyano, kanye nokusebenza kwe-carboxylate, konke kuboshwe kwi-ion ye-chloride. Le nhlanganisela isebenza njengesixhumi esibalulekile ekuhlanganisweni kwezinto eziphilayo, ikhuthaza ukuthuthukiswa kwemithi ehlukahlukene kanye namakhemikhali ezolimo. Isakhiwo sayo esiyingqayizivele kanye namaqembu asebenzayo kuyenza ibe yisisekelo sokwakha esiguquguqukayo sokwenza ama-molecule ngezinhlelo zokusebenza ezahlukahlukene, okukhuthaza ukusungula izinto ezintsha emikhakheni eminingi.
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![i-methyl imidazo[1,5-a]pyridine-7-carboxylate CAS:1377829-50-9](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU180.png)
i-methyl imidazo[1,5-a]pyridine-7-carboxylate CAS:1377829-50-9
I-Methyl imidazo[1,5-a]pyridine-7-carboxylate, ikhemikhali ehlanganiswe nefomula yama-molecule i-C9H7N3O2, yaziwa ngokusetshenziswa kwayo okuhlukahlukene emikhakheni yesayensi yezemithi nezinto zokwakha. Iqukethe uhlaka lwe-imidazo-pyridine, iveza izici zesakhiwo ezihlukile ezifaka isandla ekusetshenzisweni kwayo okuhlukahlukene. Le nhlanganisela isebenza njengesikhungo esibalulekile ekuhlanganisweni kwezinto eziphilayo, isebenza njengesisekelo sokuthuthukiswa kwemithi nezinto zokusebenza. Isakhiwo sayo esihlukile kanye nokusabela kwayo kuyenza ibe yingxenye ebalulekile ocwaningweni oluhlukahlukene kanye nemizamo yezimboni, iqhuba ukusungula izinto ezintsha emikhakheni ehlukene.
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I-Arg34GLP-1 CAS:1169630-82-3
I-Arg34GLP-1, eyaziwa nangokuthi i-Arginine-34 Glucagon-Like Peptide 1, iyi-hormone ye-peptide esebenzayo enemiphumela ebalulekile ekulawulweni kwe-metabolic kanye nokungenelela kokwelapha isifo sikashukela kanye nokukhuluphala. Le peptide itholakala ku-hormone ye-glucagon-like peptide 1 (GLP-1) futhi ine-arginine residue endaweni engu-34. Isakhiwo sayo sama-molecule kanye nemisebenzi yayo yezinto eziphilayo kwenza kube yinto ethembisayo yokusetshenziswa kwemithi okuhloswe ngayo ukuthuthukisa i-glucose homeostasis nokukhuthaza ukwehla kwesisindo.
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I-1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate CAS:1016258-66-4
I-1-tert-Butyl 4-ethyl 4-cyanopiperidine-1,4-dicarboxylate iyinhlanganisela yamakhemikhali eyaziwa ngokusetshenziswa kwayo okuhlukahlukene ezimbonini zemithi kanye nezolimo. Ngefomula yama-molecule i-C15H24N2O4, ikhombisa ukuhlelwa kwesakhiwo okuhlukile okunendandatho ye-piperidine ethathelwe indawo amaqembu e-tert-butyl, ethyl, kanye ne-cyano. Le nhlanganisela isebenza njengesixhumi esibalulekile ekuhlanganisweni kwezinto eziphilayo, idlala indima ebalulekile ekuthuthukisweni kwemithi ehlukahlukene kanye namakhemikhali ezolimo. Iphethini yayo yokushintshanisa amasu kanye namaqembu asebenzayo kuyenza ibe yisisekelo sokwakha esiguquguqukayo sokwenza izakhiwo zama-molecule eziyinkimbinkimbi ngezakhiwo ezifiselekayo zezinhlelo zokusebenza ezahlukahlukene.
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![I-6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride CAS:1956310-17-0](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M117.png)
I-6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride CAS:1956310-17-0
I-6-Chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride, eyaziwa kakhulu ngokuthi i-compound X, iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezahlukahlukene embonini yezokwelapha kanye nesayensi yezinto ezibonakalayo. Ngefomula yama-molecule ye-C8H8ClNO•HCl, le nhlanganisela ine-scaffold ye-benzo[b][1,4]oxazine ehlukile efakwe esikhundleni se-athomu ye-chlorine. Isakhiwo sayo esihlukile siyenza ibe yindawo ebalulekile yokwenziwa kwezinto eziphilayo, esebenza njengesisekelo sokuthuthukiswa kwemithi ehlukahlukene kanye nezinto ezisebenzayo.
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I-8-Methylquinazolin-4(3H)-one CAS:19181-54-5
I-8-Methylquinazolin-4(3H)-one iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezahlukahlukene kumakhemikhali ezokwelapha kanye nocwaningo lwemithi. Ngefomula yayo yama-molecule C9H8N2O, ingeyesigaba sama-compound e-quinazolinone futhi ikhombisa izakhiwo ezihlukile ze-physicochemical ezenza ibe usizo emizamweni yokuthola imithi kanye nezifundo zobudlelwano besakhiwo nomsebenzi ekuthuthukisweni kwezidakamizwa ezintsha zokwelapha.
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5,6-Difluoro-2,3-dihydro-1H-isoindol-1-one CAS:1192040-50-8
I-5,6-Difluoro-2,3-dihydro-1H-isoindol-1-one, eyaziwa ngezakhiwo zayo eziguquguqukayo, isebenza njengenhlanganisela ebalulekile kokubili ocwaningweni kanye nasezindaweni zezimboni. Ngefomula yamakhemikhali i-C8H6F2NO, ifaka ingqikithi ye-isoindolone ehlukile ethathelwe indawo ngama-athomu amabili e-fluorine, okunikeza izici ezihlukile esakhiweni sayo. Le nhlanganisela ithola ukusetshenziswa kuzo zonke izinkambu ezahlukahlukene ngenxa yokusabela kwayo okuhlukahlukene kanye nekhono lokuhlanganisa ama-molecule ayinkimbinkimbi anokubaluleka kwesayensi yezemithi kanye nezinto ezibonakalayo.
