I-Diethylacetamidomalonate CAS:1068-90-2

I-Diethylacetamidomalonate isetshenziswa kabanzi kumakhemikhali e-organic njengesisekelo sokwakhiwa kwamakhemikhali e-heterocyclic, imithi, amakhemikhali ezolimo, kanye nemikhiqizo yemvelo eyinkimbinkimbi. Isebenza njengesandulela esibalulekile ekukhiqizweni kwama-pyrazoles, ama-pyridines, kanye nezinye izinto eziqukethe i-nitrogen ezinemisebenzi yezinto eziphilayo. Ukuguquguquka kwe-diethylacetamidomalonate kuvumela osokhemisi ukuthi bethule amaqembu ahlukahlukene asebenzayo kanye nezinto ezi-stereochemical kuma-molecule, okuvumela ukuhlola izakhiwo ezintsha ngezinhlelo zokwelapha ezingaba khona. Ocwaningweni lwemithi, i-diethylacetamidomalonate isetshenziswa ekwakhiweni nasekuhlanganisweni kwezidakamizwa ezihlose izifo ezahlukahlukene njengomdlavuza, izifo ezithathelwanayo, kanye nezinkinga zezinzwa. Amandla ayo okubhekana nezinhlobo eziningi zokusabela kwenza kube yindawo ebalulekile yokwakha imitapo yolwazi yama-molecule yokuhlola okuphezulu kanye nokwenza ngcono i-lead ezinhlelweni zokuthola izidakamizwa. Ngaphezu kwalokho, ukuba khona kokusebenza kwe-ester kanye ne-amide ku-diethylacetamidomalonate kunikeza amathuba okushintsha izakhiwo ze-pharmacokinetic kanye nokuthuthukisa amandla emithi kanye nokukhetha. Sekukonke, ukusetshenziswa okuhlukahlukene kwe-diethylacetamidomalonate ekuhlanganisweni kwezinto eziphilayo kanye nokuthuthukiswa kwemithi kugqamisa ukubaluleka kwayo ekuthuthukiseni ulwazi lwesayensi kanye nokufaka isandla ekutholakaleni kwezindlela zokwelapha ezintsha ezithuthukisiwe ngempumelelo kanye namaphrofayili okuphepha.