I-Diammineplatinum(II) nitriteCAS:14286-02-3

I-Cisplatin iyi-ejenti ye-chemotherapy esetshenziswa kabanzi ekwelapheni izinhlobo ezahlukene zomdlavuza, okuhlanganisa umdlavuza wamasende, wesibeletho, wesinye, kanye nowamaphaphu. Isebenza ngokwakha izixhumanisi ze-intrastrand ku-DNA, okuholela ekuvinjelweni kokuphindaphindwa kwe-DNA kanye nokubhalwa kwayo, ekugcineni okubangela i-apoptosis kumaseli omdlavuza. Ukusebenza kwayo kahle ekwelapheni izinhlobo ezithile zomdlavuza kwenze kwaba ngomunye wemithi yomdlavuza ebaluleke kakhulu futhi esetshenziswa kabanzi emtholampilo. Ngaphezu kokusetshenziswa kwayo njenge-ejenti ye-chemotherapy, i-cisplatin iphinde yahlolwa ngezicelo zayo ezingaba khona emkhakheni we-chemistry yezokwelapha. Imizamo yocwaningo igxile ekwakheni imithi emisha esekelwe ku-platinum enempumelelo ethuthukisiwe, ubuthi obuncishisiwe, kanye nomsebenzi obanzi wokulwa nezinhlobo ezahlukene zomdlavuza. Ngaphezu kwalokho, i-cisplatin iphinde yahlolwa ngokusetshenziswa kwayo okungaba khona ekwelashweni okuhlangene nezinye izidakamizwa zokulwa nomdlavuza ukuthuthukisa imiphumela yokwelashwa nokunciphisa ukumelana nemithi. Ngaphezu kwalokho, i-cisplatin ihlolwe ngezicelo zayo emkhakheni wesayensi yezinto kanye ne-nanotechnology. Isetshenziswe ekuhlanganiseni ama-nanoparticles nama-nanomaterials aqukethe i-platinum anezicelo ezingaba khona ekulethweni kwemithi, ekuthathweni kwezithombe, nasekuzweleni. I-reactivity eyingqayizivele kanye ne-coordination chemistry ye-cisplatin iyenza ibe yindaba ethakazelisayo ekuthuthukiseni izinto ezintsha kanye nezicelo ze-nanotechnological. Ngamafuphi, i-diammineplatinum(II) nitrite, noma i-cisplatin, iyisidakamizwa esisetshenziswa kabanzi sokulwa nomdlavuza esinezicelo ezingaba khona kumakhemikhali wezokwelapha, isayensi yezinto, kanye ne-nanotechnology. Indawo yayo eyingqayizivele yokuxhumanisa kanye ne-reactivity yenza ibe yindaba ethakazelisayo ekuthuthukiseni izinto ezintsha zokwelapha, izinto ezisebenzayo, kanye nezicelo ze-nanotechnological.