I-Dehydrogenase, utshwala CAS: 9031-72-5 Intengo Yomkhiqizi

Ama-dehydrogenase ayiqembu lama-enzyme avuselela ukujiya kwe-substrate ngokususa ama-athomu e-hydrogen. Uma kukhulunywa nge-alcohol dehydrogenase, isebenza ngqo kuma-alcohol, ikhuthaze ukuguqulwa kwawo abe ama-aldehyde noma ama-ketone ngokususa ama-athomu e-hydrogen.

Ngokuphathelene nomphumela wotshwala, i-alcohol dehydrogenase idlala indima ebalulekile ekusetshenzisweni kwe-ethanol emzimbeni womuntu. Isiza ekuhlukaniseni i-ethanol ibe yi-acetaldehyde, bese iguqulwa ibe yi-acetic acid. Le nqubo ibalulekile ekuvimbeleni ukuqongelela kwamazinga anobuthi e-ethanol emzimbeni. Kodwa-ke, ukuphuza utshwala ngokweqile kungadlula amandla e-alcohol dehydrogenase, okuholela ekuqongeleleni kwe-acetaldehyde, ehlotshaniswa nezimpawu ezingathandeki ezaziwa ngokuthi ukusabela kwe-alcohol flush.

Ngokuphathelene nokusetshenziswa, i-alcohol dehydrogenase inezindlela eziningana ezibalulekile zokusetshenziswa. Ivame ukusetshenziswa ekukhiqizweni kwe-ethanol embonini yokubilisa. Le enzyme isetshenziswa ukugqugquzela ukuguqulwa koshukela ube yi-ethanol yimvubelo noma amabhaktheriya. Ngaphezu kwalokho, i-alcohol dehydrogenase isetshenziswa ezindleleni ezahlukene zelebhu kanye nokuhlolwa kokuxilonga. Isetshenziselwa ukukala amazinga otshwala ekuhlolweni kwe-breathalyzer kanye nokuhlolwa kokuqukethwe kotshwala egazini (i-BAC). Ngaphezu kwalokho, ithola ukusetshenziswa ekukhiqizweni kwamakhemikhali, njenge-organic acid kanye nama-ester, ngezinqubo ze-biocatalysis.