I-Colistin Sulfate CAS:1264-72-8

I-Colistin sulfate isetshenziswa ekuphatheni izifo ezingathi sína zamagciwane ezibangelwa amagciwane angenawo umuthi amaningi. Ivame ukugcinelwa ukwelapha izifo ezifana ne-pneumonia ehlobene nokuphefumula, i-sepsis, izifo zomgudu womchamo, kanye nokutheleleka kwegazi lapho kubangelwa amagciwane afana ne-Pseudomonas aeruginosa, i-Acinetobacter baumannii, kanye ne-Klebsiella pneumoniae. Umthamo ofanele kanye nokuphathwa kwe-colistin sulfate kubalulekile ukuze kufezwe imiphumela emihle yokwelashwa ngenkathi kunciphisa ingozi yemiphumela emibi. Ngenxa yokuthi inamandla okuba nesifo se-nephrotoxicity kanye ne-neurotoxicity, ukuqapha eduze ukusebenza kwezinso kanye nesimo sezinzwa kubalulekile ngesikhathi sokwelashwa. Ukulungiswa komthamo kungadingeka ngokusekelwe ezicini zesiguli ngasinye kanye nokusebenza kwezinso. Abahlinzeki bezempilo kufanele benze ukuhlolwa kokuzwela ngaphambi kokuqala ukwelashwa nge-colistin sulfate ukuqinisekisa ukumbozwa okufanele kwesitho esithelelanayo. Ukusabela okubi kungafaka ukukhubazeka kwezinso, izinkinga zokuphefumula, kanye nokusabela kokuzwela, okudinga ukuqapha ngokucophelela phakathi nayo yonke inkambo yokwelashwa. Ekuphetheni, i-colistin sulfate idlala indima ebalulekile ekulweni nokutheleleka okubangelwa amagciwane angenawo umuthi amaningi futhi kufanele isetshenziswe ngokuhlakanipha ukuze kulondolozwe ukusebenza kwayo nokunciphisa ukuthuthukiswa kokumelana okwengeziwe. Ukunamathela ezimisweni zokuphatha ama-antimicrobial kubalulekile ekusetshenzisweni okufanele kwe-colistin sulfate ukuze kuthuthukiswe imiphumela yeziguli futhi kuvinjelwe ukusabalala kwezinhlobo ezimelana namagciwane.