I-Colistin sodium methanesulfonate evela ku-bacillus colistinus CAS:8068-28-8

I-Colistin sodium methanesulfonate isetshenziswa kakhulu ekuphatheni izifo ezinkulu zamagciwane ezibangelwa amagciwane angenawo amagremu, ikakhulukazi izinhlobo ezimelana nezinhlobo eziningi zama-antibiotic. Ivame ukusetshenziswa ezimweni ze-pneumonia etholwa esibhedlela, i-pneumonia ehlobene nokuphefumula, i-sepsis, kanye nokutheleleka komgudu womchamo lapho kubangelwa amagciwane angamelana nemithi eminingi njenge-Pseudomonas aeruginosa, i-Acinetobacter baumannii, kanye ne-Klebsiella pneumoniae. Umthamo ofanele kanye nokuphathwa kwe-colistin sodium methanesulfonate kubalulekile ekufinyeleleni imiphumela emihle yokwelapha. Ngenxa yokuthi inamandla okuba yingozi kanye nobuthi be-neurotoxicity, ukuqapha eduze ukusebenza kwezinso kanye nesimo sezinzwa kubalulekile ngesikhathi sokwelashwa. Ukulungiswa komthamo kungadingeka ngokusekelwe ekusebenzeni kwezinso kanye nezici zesiguli ngasinye. Ngaphambi kokusebenzisa i-colistin sodium methanesulfonate, abahlinzeki bezempilo kufanele bahlole ukuthambekela kwento ethelelanayo ukuqinisekisa ukwelashwa okufanele. Imiphumela emibi ingafaka ukukhubazeka kwezinso, izinkinga zokuphefumula, kanye nokusabela kokungezwani komzimba, okudinga ukuqapha okuqaphile phakathi nesikhathi sokwelashwa. Ngamafuphi, i-colistin sodium methanesulfonate iyi-antibiotic ebalulekile yokulwa nokutheleleka kwe-gram-negative okumelana nemithi eminingi futhi kufanele igcinelwe izimo lapho kungekho ezinye izinketho ezitholakalayo. Ukusetshenziswa kwayo ngokuhlakanipha, okuqondiswa yizimiso zokuphatha ama-antimicrobial, kubalulekile ukuze kulondolozwe ukusebenza kwayo nokuvimbela ukuvela kwezindlela ezengeziwe zokumelana.