I-Capreomycin sulfate (i-Capastat sulfate) I-CAS:1405-37-4

I-Capreomycin sulfate (i-Capastat sulfate) iyisici esibalulekile ekuphathweni kwesifo sofuba esingamelana nemithi eminingi (i-MDR-TB), ikakhulukazi lapho imithi ejwayelekile yokuqala yokulwa nesifo sofuba ingasebenzi kahle. Isetshenziswa njengengxenye yezindlela zokwelapha ezihlanganisiwe ukubhekisisa nokwelapha izinhlobo zesifo sofuba i-Mycobacterium ezingamelana nemithi. Ukunikezwa kwe-Capreomycin sulfate kuhilela imijovo engaphakathi kwesisu noma ejulile, ngokuvamile ngaphansi kokugadwa kochwepheshe bezempilo abanolwazi ekuphatheni isifo sofuba. Ukwelashwa nge-Capreomycin sulfate kudinga ukubhekwa ngokucophelela ngenxa yemiphumela emibi engaba khona ehlotshaniswa nama-antibiotic e-aminoglycoside, okuhlanganisa ubuthi bezinso kanye nokukhubazeka kokuzwa. Umthamo kanye nobude bokwelashwa kunqunywa ngokwesimo sesiguli, isisindo, ukusebenza kwezinso, kanye nokusabela ekwelashweni. Iziguli ezithola ukwelashwa nge-Capreomycin sulfate ziyalulekwa ukuthi zinamathele ngokuqinile ohlelweni lokwelashwa olunqunyiwe ukuze zikhuphule ukusebenza kwayo futhi zinciphise ingozi yokumelana nemithi eyengeziwe. Ukuqapha njalo imiphumela emibi engaba khona, kanye nokuhlolwa njalo komsebenzi wezinso kanye nokuzwa, kubalulekile ngesikhathi sokwelashwa. Ukubambisana okuseduze nabahlinzeki bezempilo kanye nokunamathela ngokuqinile eselulekweni sezokwelapha kubalulekile ekuphathweni ngempumelelo kwesifo sofuba nge-Capreomycin sulfate, okuhlose ukuqeda ngokuphelele i-MDR-TB ngenkathi kunciphisa amathuba okwehluleka kokwelashwa noma ukubuyela emuva.