I-Capastat sulfate (i-Capreomycin sulfate) I-CAS:1405-37-4

I-Capastat sulfate (i-Capreomycin sulfate) idlala indima ebalulekile ekuphathweni kwesifo sofuba esingamelani nemithi eminingi, uhlobo lwesifo sofuba olungamelani nemithi ejwayelekile yokulwa ne-TB yomugqa wokuqala. Ivame ukusetshenziswa kanye neminye imithi yomugqa wesibili ukuze ihlose futhi yelaphe ngempumelelo ukutheleleka kwe-MDR-TB. Ngenxa yomsebenzi wayo wokubulala amagciwane ngokumelene nezinhlobo ze-Mycobacterium tuberculosis ezingamelana nemithi yomugqa wokuqala njenge-isoniazid ne-rifampin, i-Capastat sulfate igcinelwe izimo lapho ukwelashwa okuvamile kwe-TB kungaphumelelanga khona. Ukwelashwa nge-Capastat sulfate kuvame ukunikezwa ngaphansi kokuqondisa kochwepheshe bezempilo abanolwazi ekuphatheni isifo sofuba esingamelana nemithi. Umthamo kanye nobude bokwelashwa kwe-Capastat sulfate kulungiselelwe izidingo zesiguli ngasinye ngokusekelwe ezicini ezifana nobunzima bokutheleleka, isisindo sesiguli, kanye nokusebenza kwezinso. Ukuqapha njalo ukusebenza kwezinso kanye nokuzwa kubalulekile ngesikhathi sokwelashwa, njengoba ama-antibiotic e-aminoglycoside njenge-Capreomycin angabangela ukulimala kwezinso kanye nokulahlekelwa ukuzwa. Iziguli ezithola ukwelashwa kwe-Capastat sulfate kufanele zilandele uhlelo lwazo lokwelashwa olunqunyiwe ngenkuthalo ukuze zifinyelele imiphumela emihle futhi zinciphise ingozi yokukhula kokumelana okwengeziwe. Ukunamathela enkambisweni ephelele yokwelashwa kubalulekile ukuqinisekisa ukuqeda ngokuphelele i-MDR-TB nokunciphisa amathuba okwehluleka kokwelashwa noma ukubuyela emuva. Kunconywa ukuqapha ngokucophelela noma yimiphi imiphumela emibi kanye nokuhlolwa okulandela njalo nabahlinzeki bezempilo ukuze kulawulwe imiphumela emibi engaba khona futhi kuthuthukiswe izinzuzo zokwelapha ze-Capastat sulfate ekulweni nesifo sofuba esingamelana nemithi.