I-Boc-Leu-OSu CAS: 3392-09-4

I-Boc-Leu-OSu isetshenziswa kabanzi emasu okuhlanganisa i-bio kanye nezinqubo zokuguqula i-peptide. Ekuhlanganisweni kwe-peptide, kwenza kube lula ukufakwa okulawulwayo kwezinsalela ze-leucine kuchungechunge lwe-peptide, okuvumela ukunamathiswa okuqondiwe kwamaqembu ahlukahlukene asebenzayo, amalebula, noma ama-molecule ukuze kusetshenziswe izinhlelo ezahlukene. Lokhu kuguqulwa okukhethiwe kuvumela ukudalwa kwama-peptide asebenzayo amaningi anezakhiwo ezilungiselelwe, njengokuqina okuthuthukisiwe, ukucaciswa okuqondiwe, noma amakhono okuthwebula izithombe. Ocwaningweni lwe-proteomics, i-Boc-Leu-OSu ivumela ukulebula kwamaprotheni nama-peptide endaweni ethile, okufaka isandla ekuhlaziyweni kwesakhiwo, izifundo zokusebenzisana, kanye nokuhlolwa okusekelwe ku-mass spectrometry. Ukunamathiswa okulawulwayo kwe-Boc-Leu-OSu ezinsaleleni ze-leucine kwenza kube lula ukuchaza okunembile kanye nokuhlaziywa kokusebenza kwamaprotheni nama-peptide, kusekela intuthuko ekuqondeni izinhlelo zezinto eziphilayo kanye nezindlela zesifo. Ngaphezu kwalokho, ekuthuthukisweni kwemithi, i-Boc-Leu-OSu idlala indima ebalulekile ekuhlanganiseni izinto zokwelapha kuma-peptide noma ama-protein, ukudala izinhlelo zokulethwa kwemithi eziqondiwe, ama-antibody-drug conjugates, noma ukwakha imijovo enephrofayili ye-pharmacokinetic ethuthukisiwe kanye nemiphumela encishisiwe engaqondiwe. Sekukonke, ukuthembeka kanye nokuguquguquka kwe-Boc-Leu-OSu ekuguqulweni kwe-peptide kanye ne-bioconjugation kwenza kube ithuluzi elibalulekile lokuthuthukisa ucwaningo ekutholakaleni kwezidakamizwa, i-chemistry biology, kanye ne-proteomics, okunikeza amathuba ahlukahlukene okuthuthukisa izinhlelo zokusebenza ezintsha ze-biomedical.