I-Boc-D-Asn-ONp CAS:104199-82-8

I-Boc-D-Asn-ONp isetshenziswa kakhulu ekuhlanganisweni kwe-peptide njenge-ester esebenzayo yokuhlanganiswa okuphumelelayo kwe-D-asparagine namanye ama-amino acid ngesikhathi sokuhlanganiswa kwe-peptide yesigaba esiqinile (i-SPPS). Indima yayo ekwenzeni kube lula ukuhlanganiswa okulawulwayo kwama-peptide ekusekelweni okuqinile ibalulekile ekuthuthukisweni kokulandelana kwe-peptide okwenziwe ngokwezifiso ngemisebenzi ethile yezinto eziphilayo, okufaka isandla ekutholakaleni kwezidakamizwa, izifundo ze-biochemical, kanye nokucaciswa kokusebenzisana kwamaprotheni kanye nezindlela zokubonisa izimpawu. Ngaphezu kwalokho, i-Boc-D-Asn-ONp idlala indima ebalulekile ekudalweni kwemitapo yolwazi ye-peptide yokuhlola izidakamizwa nokwenza ngcono i-lead. Ubumsulwa bayo obuphezulu kanye nekhwalithi ehambisanayo kuqinisekisa ukuthembeka nokuphindaphinda ezinqubweni zocwaningo, okwenza kube ithuluzi eliwusizo kososayensi nabacwaningi kuzo zonke izinkambu ezahlukahlukene, kusukela ocwaningweni oluyisisekelo kuya ekuthuthukisweni kwemithi emisha kanye namakhemikhali e-bioactive. Ngamafuphi, i-Boc-D-Asn-ONp ibalulekile ekuthuthukisweni kokutholwa kwesayensi nezokwelapha ngokuvumela ukuhlanganiswa kwama-peptide ayinkimbinkimbi anezakhiwo ezilungiselelwe, ekugcineni isekele ukuthuthukiswa kwemithi emisha kanye nezidakamizwa zokwelapha. Ukuguquguquka kwayo kanye nokusetshenziswa kwayo kabanzi ocwaningweni lwemithi kugcizelela ukubaluleka kwayo njengethuluzi eliwusizo kososayensi nabacwaningi emhlabeni jikelele.